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differentially expressed in lymphoblasts from patients with probable or definite AD. This novel strategy identified changes in 6 transcripts, including the lipoprotein receptor LR11 (LDL receptor relative with 11 ...
) using standard protocols. Brain tissue was obtained during clinically indicated epilepsy surgery and appropriate samples were analysed by our molecular methods. Brain MRI All subjects underwent brain MRI ...
nuclei with glioma-like expression profiles did not harbor detectable CNVs. Differential gene expression analysis identified several molecular and signaling pathways that distinguish CNV+ glioma cells from ...
regulates differential sorting of APP into the retromer recycling pathway, thus reducing Aβ production; when expression of SORL1 is reduced, APP trafficking is directed toward endosome-lysosome compartments ...
and thermogenesis (45). Bone morphogenetic proteins (BMPs) are also known to promote brown and beige fat differentiation and thermogenesis (66, 67). For example, BMP8b is a BMP family member that is expressed ...
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