Detailed assessments of childhood adversity enhance prediction of central obesity independent of gender, race, adult psychosocial risk and health behaviors

Detailed assessments of childhood adversity enhance prediction of central obesity independent of... 1 Introduction</h5> Obesity, especially central adiposity, and metabolic syndrome (MetS) place adults at high risk for other physical health problems, especially diabetes mellitus (DM), cardiovascular disease (CVD), and hypertension [1–9] . Central obesity has been associated with early stressful environments and events [10–13] , including intra-uterine stresses and early illnesses [14,15] , poverty [16] , and specific and cumulative stresses such as physical and sexual abuse in childhood or death of a close family member [17–20] , in both animal models and human studies [14,21–23] . Psychosocial factors including socioeconomic status (SES), education, and functional status (adjustment or functioning in the domains of mental health, work, leisure/interests, and close relationships) provide a mediated link between early life stressors and later health [12,16,24–27] . Impaired psychosocial functioning is associated with health risk factors [28,29] , such as smoking, drinking, poor diet, and sedentary lifestyle that set the stage for poor health outcomes in general.</P>Many psychosocial factors and health risk factors are considered modifiable, with the potential to decrease obesity rates and costs [30] , and are the focus of many prevention/intervention programs. However, it is rare for such programs to assess childhood adversity and its potential direct, non-mediated impact http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Metabolism Elsevier

Detailed assessments of childhood adversity enhance prediction of central obesity independent of gender, race, adult psychosocial risk and health behaviors

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Publisher
Elsevier
Copyright
Copyright © 2014 Elsevier Inc.
ISSN
0026-0495
DOI
10.1016/j.metabol.2013.08.013
pmid
24211017
Publisher site
See Article on Publisher Site

Abstract

1 Introduction</h5> Obesity, especially central adiposity, and metabolic syndrome (MetS) place adults at high risk for other physical health problems, especially diabetes mellitus (DM), cardiovascular disease (CVD), and hypertension [1–9] . Central obesity has been associated with early stressful environments and events [10–13] , including intra-uterine stresses and early illnesses [14,15] , poverty [16] , and specific and cumulative stresses such as physical and sexual abuse in childhood or death of a close family member [17–20] , in both animal models and human studies [14,21–23] . Psychosocial factors including socioeconomic status (SES), education, and functional status (adjustment or functioning in the domains of mental health, work, leisure/interests, and close relationships) provide a mediated link between early life stressors and later health [12,16,24–27] . Impaired psychosocial functioning is associated with health risk factors [28,29] , such as smoking, drinking, poor diet, and sedentary lifestyle that set the stage for poor health outcomes in general.</P>Many psychosocial factors and health risk factors are considered modifiable, with the potential to decrease obesity rates and costs [30] , and are the focus of many prevention/intervention programs. However, it is rare for such programs to assess childhood adversity and its potential direct, non-mediated impact

Journal

MetabolismElsevier

Published: Feb 1, 2014

References

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