Journal of Colloid and Interface Science 516 (2018) 332–341 Contents lists available at ScienceDirect Journal of Colloid and Interface Science journal homepage: www.elsevier.com/locate/jcis Regular Article Design and evaluation of galactosylated chitosan/graphene oxide nanoparticles as a drug delivery system a,⇑ b c a a a Chen Wang , Zhiqiang Zhang , Binbin Chen , Liuqiong Gu , Yuan Li , Shuwei Yu School of Pharmacy, Xiamen Medical College, Xiamen 361023, PR China Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, PR China Department of Pharmacy, Xiamen Xianyue Hospital, 361012, PR China graphical a bstract ar ti c l e i nf o ab stra ct Article history: We investigated a novel drug delivery system comprising nanoparticles based on galactosylated chi- Received 21 November 2017 tosan/graphene oxide/doxorubicin (GC–GO–DOX) for the therapeutic treatment of cancer. The drug deliv- Revised 18 January 2018 ery system was synthesized by loading a drug sample with galactosylated chitosan (GC) on a graphene Accepted 19 January 2018 oxide (GO) carrier. The results showed that the drug loading capacity was as high as 1.08 mg/mg (drug Available online 31 January 2018 per polymer). The nanoparticles remained stable under physiological conditions, and the drug was released
Journal of Colloid and Interface Science – Elsevier
Published: Apr 15, 2018
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera