•The S protein of PDEV was displayed on the surface of a recombinant Lactobacillus plantarum NC8 strain.•NC8-pSIP409-pgsA'-S-DCpep promoted DC activation in the LP.•IgG and sIgA were significant increased in mice orally administered with the NC8-pSIP409-pgsA'-S-DCpep.•The expression of specificity cytokines IFN-γ, IL-4 and IL-17A of MLNs was enhanced in mouse treated with the NC8-pSIP409-pgsA'-S-DCpep.•NC8-pSIP409-pgsA'-S-DCpep might mediate B cell response in mouse.
Virus Research – Elsevier
Published: Mar 2, 2018
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