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(human, chicken, mouse , pig, cattle). Chimeric TLR5 receptors, consisting of human transmembrane and intracellular domains , linked to extracellular domains of animal origin, were generated and expressed ...
cells. Among these molecules, the CTLA-4 extracellular region (CTLA-4 IgV) may be used as a novel immune adjuvant molecule for delivering antigens and inducing strong humoral and cellular immune responses ...
It is believed that mouse FcγRIII arose by an evolutionarily recent recombination, which brought together the extracellular domains from FcγRII with the transmembrane/cytoplasmic region from ...
activities are defined for a particular modification of the extracellular domain of TNF but a direct comparison of different mutant memTNF molecules has not been done in vivo . Methodology To understand ...
Immune response genes1,2 of the murine major histocompatibility complex encode cell-surface glycoproteins that are expressed predominantly on B cells and macrophages and regulate immune ...
the extracellular domains of both mouse PD-1 and PD-L1 were replaced with the corresponding human sequences. Using this new model, we sought to compare the strength of the immune response generated by Food and Drug ...
comparison poet hoc test. All data are pooled from three independent experiments. *P ...
are responsible for various innate immune dysfunctions due to abnormal structure or expression of human MBL‐C. In these studies, we identified SNPs in the expressed collagenous lectin genes Mbl1, Mbl2, Fcna ...
Natural killer (NK) cells are essential components of the innate immune response to tumors and viral infections. In humans, the activating natural cytotoxicity receptor NKp30 plays a major role in NK ...
Abstract Background Abnormal innate immune response contributes to inflammatory bowel disease (IBD) and experimental mouse colitis. Colitis studies have focused primarily on key regulators of innate ...
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