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). These hormones are usually determined in plasma samples as parameters of adrenal activity and thus of disturbance. GCs (and CAs) are extensively metabolized and excreted afterwards. Therefore, the concentration ...
of the metabolic abnormalities reported by our group. IL‐1, when administered intracerebroventricularly to experimental animals, appears to have enhanced biological activity compared to that administered ...
). References 1 Lloyd CW. Some clinical aspects of adrenal cortical and fluid metabolism . Recent Prog Horm Res 1952 ; 7 : 469 -510. 2 Hatfield CB, Shuster S. The significance of changes in plasma cortisol ...
For more than four decades, the measurement of free cortisol excretion in the urine (UFC) has been considered a reliable test for the diagnosis of Cushing's syndrome (1). Over time, assay ...
Induction of cytochrome P450 3A (CYP3A) has been suggested as a mechanism of action of ursodeoxycholic acid (UDCA) in cholestasis. CYP3A is of key importance in human drug metabolism , being involved ...
. Postmenopausal women (49–75 years old) with high (n = 41) or low (n = 37) dietary restraint were compared to examine differences in urinary cortisol excretion , body composition assessed by dual-energy x-ray ...
Table. Higher urinary excretion values during the day compared to night time have been found for cortisol and cortisone and for almost all glucocorticoid metabolites in both sexes. During the day higher ...
aldosterone and renin results. Apparent mineralocorticoid excess syndrome and chronic licorice ingestion were excluded on the basis of normotension and her 24-h urine cortisol excretion being within ...
of the metabolic syndrome and type 2 diabetes mellitus (T2DM) in patients with PA (8). However, some aspects of impairment of glucose homeostasis in PA are still unresolved. In the past, cortisol cosecretion in PA ...
to produce glucocorticoids (GCs), mainly cortisol in muskoxen [8]. Free GCs circulating in the plasma are primarily metabolized by the liver, and the resulting metabolites are excreted via the bile ...
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