Veterinary Microbiology 220 (2018) 24–32 Contents lists available at ScienceDirect Veterinary Microbiology journal homepage: www.elsevier.com/locate/vetmic Clinical course and pathogenicity of variant rabbit haemorrhagic disease virus in experimentally infected adult and kit rabbits: Signiﬁcance towards control and spread a b b a a a b K.P. Dalton , A. Balseiro , R.A. Juste , A. Podadera , I. Nicieza , D. del Llano , R. González , a b a b, J.M. Martin Alonso , J.M. Prieto , F. Parra , R. Casais Instituto Universitario de Biotecnología de Asturias, Departamento de Bioquímica y Biología Molecular, Ediﬁcio Santiago Gascón, Universidad de Oviedo, Campus El Cristo, 33006, Oviedo, Spain SERIDA, Servicio Regional de Investigación y Desarrollo Agroalimentario (SERIDA), Centro de Biotecnología Animal, 33394, Gijón, Asturias, Spain ARTIC L E I NF O ABSTRAC T Keywords: RHDVb has become the dominant RHDV on the Iberian Peninsula. A better understanding of its pathogenicity is Clinical course required to aid control measures. Thus, the clinical course, humoral immune response, viraemia and kinetics of Immune response RHDV-N11 (a Spanish RHDVb isolate) infection in diﬀerent tissues at both viral RNA and protein levels were Viraemia studied in experimentally infected young and adult rabbits. The case fatality rate
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