Characterization of the hemagglutinin gene of subtype H9 avian influenza viruses isolated in 2007–2009 in China

Characterization of the hemagglutinin gene of subtype H9 avian influenza viruses isolated in... Subtype H9 avian influenza viruses (AIVs) circulating in China have aroused concerns for their impact on poultry and risk to public health. In this report, three surveys of the viruses were reported, and the hemagglutinin gene of 55 strains of the viruses isolated in China in 2007–2009 was sequenced and analyzed. The results indicated that the prevalence of the viruses was rising in China, and most of the H9 AIVs circulating in the past decade in China belonged to sublineage h9.4.2. The viruses isolated in China in 2007–2009 were a little different from previous strains (genetic distances >7.1%). Meanwhile, a presumably predominant clade of the viruses circulating in China in 2007–2009 was identified. Mutation analysis suggested that the viruses have become of greater risk to public health in recent years. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Virological Methods Elsevier

Characterization of the hemagglutinin gene of subtype H9 avian influenza viruses isolated in 2007–2009 in China

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Publisher
Elsevier
Copyright
Copyright © 2009 Elsevier B.V.
ISSN
0166-0934
eISSN
1879-0984
D.O.I.
10.1016/j.jviromet.2009.09.013
Publisher site
See Article on Publisher Site

Abstract

Subtype H9 avian influenza viruses (AIVs) circulating in China have aroused concerns for their impact on poultry and risk to public health. In this report, three surveys of the viruses were reported, and the hemagglutinin gene of 55 strains of the viruses isolated in China in 2007–2009 was sequenced and analyzed. The results indicated that the prevalence of the viruses was rising in China, and most of the H9 AIVs circulating in the past decade in China belonged to sublineage h9.4.2. The viruses isolated in China in 2007–2009 were a little different from previous strains (genetic distances >7.1%). Meanwhile, a presumably predominant clade of the viruses circulating in China in 2007–2009 was identified. Mutation analysis suggested that the viruses have become of greater risk to public health in recent years.

Journal

Journal of Virological MethodsElsevier

Published: Feb 1, 2010

References

  • A review of avian influenza in different bird species
    Alexander, D.J.
  • Antigenic structure of the hemagglutinin of H9N2 influenza viruses
    Okamatsu, M.; Sakoda, Y.; Kishida, N.; Isoda, N.; Kida, H.

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