Characterization of neuromedin U (NMU), neuromedin S (NMS) and their receptors (NMUR1, NMUR2) in chickens

Characterization of neuromedin U (NMU), neuromedin S (NMS) and their receptors (NMUR1, NMUR2) in... •NMU encodes NMU and NURP peptides, and NMS only encodes an NMS peptide in chickens.•cNMUR1 can be potently activated by cNMU and cNMS peptides.•cNMUR2 can be preferentially activated by cNMS peptide.•Both cNMUR1 and cNMUR2 are functionally coupled to multiple signaling pathways.•The tissue distribution of NMU, NMS, NMUR1 and NMUR2 was revealed in an avian species. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Peptides Elsevier

Characterization of neuromedin U (NMU), neuromedin S (NMS) and their receptors (NMUR1, NMUR2) in chickens

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Publisher
Elsevier
Copyright
Copyright © 2017 Elsevier Inc.
ISSN
0196-9781
D.O.I.
10.1016/j.peptides.2017.12.022
Publisher site
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Abstract

•NMU encodes NMU and NURP peptides, and NMS only encodes an NMS peptide in chickens.•cNMUR1 can be potently activated by cNMU and cNMS peptides.•cNMUR2 can be preferentially activated by cNMS peptide.•Both cNMUR1 and cNMUR2 are functionally coupled to multiple signaling pathways.•The tissue distribution of NMU, NMS, NMUR1 and NMUR2 was revealed in an avian species.

Journal

PeptidesElsevier

Published: Mar 1, 2018

References

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