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technique we were able to show that this clone contains a TPA (phorbol 12-myristate 13-acetate)- responsive element (TRE) in its first intron . This element (denoted as element X) is identical to the consensus ...
). We hypothesized that IUGR disrupts the normal developmental maturation of hepatic IGF‐1 intron 2 growth hormone response element (IN2GHRE) histone methylation of key lysines and DNA methylation. We ...
a glucocorticoid-like response element (GRE). Both deletion of, and site-specific mutations within this sequence motif reduced the dexamethasone-lnductbte activity. The GRE-iike sequence from the rat link protein ...
/840283 by DeepDyve user on 05 August 2020 J. Biochem 115, 778-788 (1994) The Delayed Glucocorticoid- Responsive and Hepatoma Cell-Selective Enhancer of the Rat Arginase Gene Is Located around Intron 71 ...
network connecting the activated GH receptor on the cell membrane to the IGF-I gene in the nucleus. Here we analyze two distinct conserved GH response elements in the rat IGF-I locus that contain ...
in any cell line tested. This is confirmed by the evidence that, upon extensive analysis, the rat GLUT1 promoter and the first intron sequence do not shows any thyroid responsive elements . Our data ...
genes contain consensus sequences for AP-1, Oct-1 and multiple copies of perfect and imperfect steroid hormone response elements (REs) (estrogen, glucocorticoid (GRE), and progesterone) which may comprise ...
. In addition to the Pit-1 sites, 21 glucocorticoid response element (GRE) half-sites and two cAMP response elements were found within the 2-kb sequence, suggesting control by hypophysiotropic hormones ...
activity. Further mapping suggested a cAMP- responsive element located between −101 and the transcription start site, and thyroid hormone - responsive elements between −1741 and −1269 and between −317 and −101 ...
the noncoding exon 1 and a short 5′ sequence of intron 1. For the rat , the core promoter spanned −581 to −469 bp, and inclusion of exon 1 and a short 5′-sequence of intron 1 reduced activity by 67%. Mutation ...
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