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when treated with kinase inhibitors such as staurosporine and H-89, indicating that these inhibitors induce a caspase -dependent apoptosis that is different from the mitochondrial pathway. CrmA, a Caspase ...
for these mitochondrial pro-apoptotic factors. In addition to caspase inhibition we assessed the effects of the Bcl-2 anti-apoptotic family on differentiation induced apoptosis . BH4-Bcl-xl-TAT recombinant protein did ...
- and caspase - independent apoptosis Cell Death and Differentiation (2004) 11, 785–787. doi:10.1038/sj.cdd.4401398 Published online 27 February 2004 Dear Editor, control, ZVAD reduced staurosporine- induced ...
and involucrin following sodium butyrate treatment. Together these results indicate that sodium butyrate is a potent inducer of Fas associated apoptosis via caspase activation in HaCaT keratinocytes, an effect ...
and (b) comment on the role of the caspases and calpains in mediating bicalutamide- induced apoptosis in androgen-dependent and androgen- independent cells. PWR-1E, PC-3 and DU-145 cells were treated ...
that caspase -dependent and caspase - independent pathways should be considered in apoptosis of myogenic cells induced by inhibition of HSP90 ATPase activity. Keywords Apoptosis · HSP90 · Mitochondria · Myogenic ...
generation. Equal doses of RO and CA used in hNSCs induced caspase 9/3‐dependent apoptosis in differentiated cultures. Time‐dependent ATP depletion occurred earlier and to a greater extent in RO‐treated hNSCs ...
taxol- induced apoptosis in leukemia U937 cells involved caspase -3 activation step. We conclude that a unique caspase -3 and caspase -9 independent pathway is elicited by taxol to induce apoptosis in human ...
the characteristics or kinetics of apoptosis , implying that retinal cell death in vitro follows a caspase - independent pathway. We have previously demonstrated the ability of reactive oxygen species (ROS) to act ...
Cell Death and Differentiation (2004) 11, 591–595 & 2004 Nature Publishing Group All rights reserved 1350-9047/04 $25.00 www.nature.com/cdd News and Commentary Apoptosis - inducing factor (AIF ...
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