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., 2008). These mutation reporter lines carrying a nonfunctional uidA gene enabled us to score somatic frameshift mutations, base substitutions, intrachromosomal recombination (ICR), and transpositions ...
) Google Scholar Crossref Search ADS PubMed WorldCat Hooker AM , Morley AA , Tilley WD , Sykes PJ . Cancer - associated genes can affect somatic intrachromosomal recombination early in carcinogenesis , Mutat ...
Introduction Triple-negative breast cancer (TNBC) comprises 15–20% of all breast cancers (BCs) and is defined by a lack of estrogen and progesterone receptor expression and the absence of ERBB2 gene ...
Abstract Grape (Vitis vinifera) color somatic variants that can be used to develop new grapevine cultivars occasionally appear associated with deletion events of uncertain origin. To understand ...
of invoking a global DNA damage response is necessary for robust activation of signaling pathways that can affect gene expression detectable on the mRNA level (Rouse and Jackson, 2002). There are several ...
is associated with the increased risk of breast cancer in human populations (2). Given the high frequency of ATM+/− heterozygous carriers in humans (3), thorough analysis of their predisposition to cancer ...
in a colorectal cancer . In total six intrachromosomal (intraChr) and seven interchromosomal (interChr) somatic rearrangement junctions were identified in the colorectal tumor (MetB7175). The junctions were ...
of the somatic homologous recombination reporter lines requires revision. Thus, more detailed information about these reporter lines is needed before they can be used with confidence to measure genome instability ...
it has been suggested that cis-splicing between adjacent genes can generate fusion transcripts in prostate cancer (7,10). To elucidate whether there was a correlation between distance and frequency we ...
, chromatin remodeling factors show their functions in gene expression through DNA methylations, histone modifications and chromatin insulations (13,14). In this process, CCCTC-binding factor (CTCF) can ...
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