Highlights ► We show that the GOA1 mutant of Candida albicans dies in high glucose. ► However, caloric restriction (CR) rescues mutant cells. ► During CR, ROS is much higher than control strains but cells survive. ► An up regulation of alternate carbon metabolism genes occurs during CR. ► We describe the relationship of CR and aging in a fungal pathogen.
Fungal Genetics and Biology – Elsevier
Published: Dec 1, 2012
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