Highlights ► Calorie restriction (CR) increases electron transport chain (ETC) at both RNA and protein level. ► CR enhances mitochondrial membrane potential, and, regardless of ages, reduces reactive oxygen species. ► CR increases both efficiency and capacity of the ETC. ► CR induces intensive modulation at mitochondrial ETC where might be a major site leading to extension of lifespan.
Biochemical and Biophysical Research Communications – Elsevier
Published: Jun 3, 2011
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