Ca 2+ -dependent regulation in neuronal gene expression

Ca 2+ -dependent regulation in neuronal gene expression Ca 2+ is an important signal-transduction molecule that plays a role in many intracellular signaling pathways. Recent advances have indicated that in neurons, Ca 2+ -controlled signaling mechanisms cooperate in order to discriminate amongst incoming cellular inputs. Ca 2+ -dependent transcriptional events can thereby be made selectively responsive to bursts of synaptic activity of specific intensity or duration. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Opinion in Neurobiology Elsevier

Ca 2+ -dependent regulation in neuronal gene expression

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Publisher
Elsevier
Copyright
Copyright © 1997 Elsevier Ltd
ISSN
0959-4388
D.O.I.
10.1016/S0959-4388(97)80072-4
Publisher site
See Article on Publisher Site

Abstract

Ca 2+ is an important signal-transduction molecule that plays a role in many intracellular signaling pathways. Recent advances have indicated that in neurons, Ca 2+ -controlled signaling mechanisms cooperate in order to discriminate amongst incoming cellular inputs. Ca 2+ -dependent transcriptional events can thereby be made selectively responsive to bursts of synaptic activity of specific intensity or duration.

Journal

Current Opinion in NeurobiologyElsevier

Published: Jun 1, 1997

References

  • Retrograde amnesia and memory consolidation: a neurobiological perspective
    Squire, LR; Alvarez, P
  • Molecular mechanisms of drug reinforcement and addiction
    Self, DW; Nestler, EJ
  • Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus
    Karin, M; Hunter, T
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    Sassone-Corsi, P
  • Transcriptional regulation by cyclic AMP
    Montminy, MR
  • Phosphorylation of CREB by CaM-kinase IV activated by CaM-kinase IV kinase
    Enslen, H; Tokumitsu, H; Soderling, TR
  • Versatile molecular glue. Transcriptional control
    Janknecht, R; Hunter, T
  • MAP kinase-dependent transcriptional coactivation of Elk-1 and its cofactor CBP
    Janknecht, R; Nordheim, A
  • Transgenic approaches to cognition
    Mayford, M; Abel, T; Kandel, ER
  • CREB and the formation of long-term memory
    Yin, JC; Tully, T
  • Spaced training induces normal long-term memory in CREB mutant mice
    Kogan, JH; Frankland, PW; Blendy, JA; Coblentz, J; Marowitz, Z; Schutz, G; Silva, AJ
  • Ca 2+ /calmodulin-dependent protein kinase kinase cascade
    Sugita, R; Mochizuki, H; Ito, T; Yokokura, H; Kobayashi, R; Hidaka, H

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