Bisphenol A: Perinatal exposure and body weight

Bisphenol A: Perinatal exposure and body weight Bisphenol A (BPA) is a component of polycarbonate and other plastics including resins that line food and beverage containers. BPA is known to leach from products in contact with food and drink, and is therefore thought to be routinely ingested. In a recent cross sectional study, BPA was detected in urine samples from 92.6% of the US population examined. The potential for BPA to influence body weight is suggested by in vitro studies demonstrating effects of BPA on adipocyte differentiation, lipid accumulation, glucose transport and adiponectin secretion. Data from in vivo studies have revealed dose-dependent and sex dependent effects on body weight in rodents exposed perinatally to BPA. The mechanisms through which perinatal BPA exposure acts to exert persistent effects on body weight and adiposity remain to be determined. Possible targets of BPA action are discussed. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Molecular and Cellular Endocrinology Elsevier

Bisphenol A: Perinatal exposure and body weight

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Publisher
Elsevier
Copyright
Copyright © 2009 Elsevier Ireland Ltd
ISSN
0303-7207
D.O.I.
10.1016/j.mce.2009.02.023
Publisher site
See Article on Publisher Site

Abstract

Bisphenol A (BPA) is a component of polycarbonate and other plastics including resins that line food and beverage containers. BPA is known to leach from products in contact with food and drink, and is therefore thought to be routinely ingested. In a recent cross sectional study, BPA was detected in urine samples from 92.6% of the US population examined. The potential for BPA to influence body weight is suggested by in vitro studies demonstrating effects of BPA on adipocyte differentiation, lipid accumulation, glucose transport and adiponectin secretion. Data from in vivo studies have revealed dose-dependent and sex dependent effects on body weight in rodents exposed perinatally to BPA. The mechanisms through which perinatal BPA exposure acts to exert persistent effects on body weight and adiposity remain to be determined. Possible targets of BPA action are discussed.

Journal

Molecular and Cellular EndocrinologyElsevier

Published: May 25, 2009

References

  • Impact of environmental chemicals on the thyroid hormone function in pituitary rat GH3 cells
    Ghisari, M.; Bonefeld-Jorgensen, E.C.
  • Bisphenol A interacts with the estrogen receptor a in a distinct manner from estradiol
    Gould, J.C.; Leonard, L.S.; Maness, S.C.; Wagner, B.L.; Conner, K.; Zacharewski, T.; Safe, S.; McDonnell, D.P.; Gaido, K.W.
  • Development of metabolic systems
    Grove, K.L.; Grayson, B.E.; Glavas, M.M.; Xiao, X.Q.; Smith, M.S.
  • Perturbed nuclear receptor signaling by environmental obesogens as emerging factors in the obesity crisis
    Grun, F.; Blumberg, B.
  • Fetal and neonatal exposure to nicotine in Wistar rats results in increased beta cell apoptosis at birth and postnatal endocrine and metabolic changes associated with type 2 diabetes
    Holloway, A.C.; Lim, G.E.; Petrik, J.J.; Foster, W.G.; Morrison, K.M.; Gerstein, H.C.
  • Thyroid hormonal activity of the flame retardants tetrabromobisphenol A and tetrachlorobisphenol A
    Kitamura, S.; Jinno, N.; Ohta, S.; Kuroki, H.; Fujimoto, N.
  • Competitive binding of xenobiotic oestrogens of rat alpha-fetoprotein and to sex steroid binding proteins in human and rainbow trout (oncorhynchus mykiss) plasma
    Milligan, S.R.; Khan, O.; Nash, M.
  • Prenatal and neonatal exposure to bisphenol-A affects the morphine-induced rewarding effect and hyperlocomotion in mice
    Mizuo, K.; Narita, M.; Miyagawa, K.; Okuno, E.; Suzuki, T.
  • Genistein affects adipose tissue deposition in a dose-dependent and gender-specific manner
    Penza, M.; Montani, C.; Romani, A.; Vignolini, P.; Pampaloni, B.; Tanini, A.; Brandi, M.L.; Alonso-Magdalena, P.; Nadal, A.; Ottobrini, L.; Parolini, O.; Bignotti, E.; Calza, S.; Maggi, A.; Grigolato, P.G.; Di Lorenzo, D.
  • Dietary xenoestrogens differentially impair 3T3-L1 preadipocyte differentiation and persistently affect leptin synthesis
    Phrakonkham, P.; Viengchareun, S.; Belloir, C.; Lombes, M.; Artur, Y.; Canivenc-Lavier, M.C.
  • Rapid endocrine disruption: environmental estrogen actions triggered outside the nucleus
    Ropero, A.B.; Alonso-Magdalena, P.; Ripoll, C.; Fuentes, E.; Nadal, A.
  • Bisphenol A affects glucose transport in mouse 3T3-F442A adipocytes
    Sakurai, K.; Kawazuma, M.; Adachi, T.; Harigaya, T.; Saito, Y.; Hashimoto, N.; Mori, C.
  • Binding and activation of the seven-transmembrane estrogen receptor GPR30 by environmental estrogens: a potential novel mechanism of endocrine disruption
    Thomas, P.; Dong, J.
  • Human exposure to bisphenol A (BPA)
    Vandenberg, L.N.; Hauser, R.; Marcus, M.; Olea, N.; Welshons, W.V.
  • The mammary gland response to estradiol: monotonic at the cellular level, non-monotonic at the tissue-level of organization?
    Vandenberg, L.N.; Wadia, P.R.; Schaeberle, C.M.; Rubin, B.S.; Sonnenschein, C.; Soto, A.M.
  • The relationship of natural killer cells to metastasis of a transplantable prostate adenocarcinoma
    Wade, A.C.; Schmidt, M.A.; Pollard, M.
  • Environmental chemicals as thyroid hormone analogues: New studies indicate that thyroid hormone receptors are targets of industrial chemicals?
    Zoeller, R.T.

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