Bioorganic & Medicinal Chemistry Letters 28 (2018) 1020–1023 Contents lists available at ScienceDirect Bioorganic & Medicinal Chemistry Letters journal homepage: www.elsevier.com/locate/bmcl Biosynthesis and in vitro enzymatic synthesis of the isoleucine conjugate of 12-oxo-phytodienoic acid from the isoleucine conjugate of a-linolenic acid a a b a a Akira Uchiyama , Takaomi Yaguchi , Hiroyuki Nakagawa , Kento Sasaki , Naoshige Kuwata , a a,⇑ Hideyuki Matsuura , Kosaku Takahashi Division of Fundamental Agroscience Research, Research Faculty of Agriculture, Hokkaido University, Kita 9, Nishi 9, Kita-ku, Sapporo 060-8589, Japan National Agriculture and Food Research Organization (NARO), Food Research Institute, 2-1-12 Kannon-dai, Tsukuba-shi, Ibaraki 305-8642, Japan ar ti c l e i nf o ab stra ct Article history: The isoleucine conjugate of 12-oxo-phytodienoic acid (OPDA-Ile), a new member of the jasmonate family, Received 10 November 2017 was recently identiﬁed in Arabidopsis thaliana and might be a signaling molecule in plants. However, the Revised 11 February 2018 biosynthesis and function of OPDA-Ile remains elusive. This study reports an in vitro enzymatic method Accepted 14 February 2018 for synthesizing OPDA-Ile, which is catalyzed by reactions of lipoxygenase (LOX), allene oxide synthase Available online 15 February 2018 (AOS), and allene oxide cyclase (AOC) using
Bioorganic & Medicinal Chemistry Letters – Elsevier
Published: Apr 1, 2018
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.
All for just $49/month
Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.
Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.
It’s easy to organize your research with our built-in tools.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera