Biologic Augmentation of Rotator Cuff Repair: The Role of Platelet-Rich Plasma and Bone Marrow Aspirate Concentrate

Biologic Augmentation of Rotator Cuff Repair: The Role of Platelet-Rich Plasma and Bone Marrow... Rotator cuff tears are common and can be a debilitating problem for patients, leading to pain, difficulty sleeping, and poor function. Although in many cases, patients can be managed non-operatively, surgery is required for a subset of patients. Even with advances in surgical techniques and implants, postoperative re-tear rates range from 15%-40%. Thus, surgical approaches to manage rotator cuff tears must be optimized to improve clinical outcomes and reduce failure rates. The incorporation of biologic agents to the repair construct has been increasingly described over the past decade, and appears to be a promising potential augmentation to standard repair techniques. Biologic agents such as platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) are obtained from the patient at the time of rotator cuff repair (RCR), and are added to the repair construct to improve the likelihood of tendon healing. This review will describe the utilization of biologic agents, including PRP and BMAC, during RCR, with an emphasis on techniques and outcomes. Given the paucity of literature describing long-term outcomes with any biologic agent as an augmentation to RCR, additional research is needed to better understand the long-term impact of these agents. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Operative Techniques in Sports Medicine Elsevier

Biologic Augmentation of Rotator Cuff Repair: The Role of Platelet-Rich Plasma and Bone Marrow Aspirate Concentrate

Loading next page...
 
/lp/elsevier/biologic-augmentation-of-rotator-cuff-repair-the-role-of-platelet-rich-bvUt1BRxsd
Publisher
Elsevier
Copyright
Copyright © 2018 Elsevier Inc.
ISSN
1060-1872
D.O.I.
10.1053/j.otsm.2017.10.008
Publisher site
See Article on Publisher Site

Abstract

Rotator cuff tears are common and can be a debilitating problem for patients, leading to pain, difficulty sleeping, and poor function. Although in many cases, patients can be managed non-operatively, surgery is required for a subset of patients. Even with advances in surgical techniques and implants, postoperative re-tear rates range from 15%-40%. Thus, surgical approaches to manage rotator cuff tears must be optimized to improve clinical outcomes and reduce failure rates. The incorporation of biologic agents to the repair construct has been increasingly described over the past decade, and appears to be a promising potential augmentation to standard repair techniques. Biologic agents such as platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) are obtained from the patient at the time of rotator cuff repair (RCR), and are added to the repair construct to improve the likelihood of tendon healing. This review will describe the utilization of biologic agents, including PRP and BMAC, during RCR, with an emphasis on techniques and outcomes. Given the paucity of literature describing long-term outcomes with any biologic agent as an augmentation to RCR, additional research is needed to better understand the long-term impact of these agents.

Journal

Operative Techniques in Sports MedicineElsevier

Published: Mar 1, 2018

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off