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Inpharma 1483 - 16 Apr 2005 ■ Atorvastatin has rapid and early anti - inflammatory effects in patients with acute coronary syndrome (ACS), report researchers from Argentina. Their study involved 90 ...
indicate that statins, a group of lipid-lowering drugs, also have extensive immunomodulatory and anti - inflammatory properties. Among statins, atorvastatin has been demonstrated as a neuroprotective agent ...
demonstrated to be risk factors for patients with acute aortic dissection (AAD). Statins have anti - inflammatory and lipid-lowering effects , which suggest that statins may play an important role in the prevention ...
in the present study. Atorvastatin is used for lowering cholesterol in primary and secondary prevention of cardiovascular disease. But, it has the pleiotropic effects such as anti - inflammatory , anti -oxidant ...
exert a beneficial effect on kidney function.4,11-13 This issue matters because acute kidney injury (AKI) associated with cardiac surgery is an important condition with a likely inflammatory component ...
that a high dose of statin has an additional anti - inflammatory effect . Table 3. Levels of inflammatory cytokines and cholesterol in serum of mice n = 8 . SAA, ng/mL . IL-6, pg/mL . TC, mmol/L . LDL, mmol/L ...
impairment of the rat/mouse models with stroke and Alzheimer’s disease, through the potential anti - inflammatory effects [17–20]. However, the effects of atorvastatin on the BBB permeability and cognition ...
of these inflammatory diseases is the production of TNF-α, which mediates a number of important events during the inflammatory immune response. TNF-α is a pleiotropic cytokine with multiple downstream effects , one ...
CW, Fichtlscherer S, Boersma E, Simoons ML. Serum level of the anti - inflammatory cytokine interleukin-10 is an important prognostic determinant in patients with acute coronary syndromes. Circulation ...
to reduce CRP levels;14–17 this effect , which appears to be dose related, may be due to reduced LDL oxidization (as a consequence of lowered LDL particle number) and/or additional anti - inflammatory activities ...
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