Assessing multiparametric drug response in tissue engineered tumor microenvironment models

Assessing multiparametric drug response in tissue engineered tumor microenvironment models •The complex tumor microenvironment is integral to affecting chemotherapeutic response.•Tissue engineering provides a simplified method for interrogating this complexity.•Our model utilizes interstitial flow for physiological chemotherapeutic dosing.•Multiple factors affecting therapeutic response can be assessed via flow cytometry. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Methods Elsevier

Assessing multiparametric drug response in tissue engineered tumor microenvironment models

Loading next page...
 
/lp/elsevier/assessing-multiparametric-drug-response-in-tissue-engineered-tumor-7gjnFzqA94
Publisher
Elsevier
Copyright
Copyright © 2017 Elsevier Inc.
ISSN
1046-2023
eISSN
1095-9130
D.O.I.
10.1016/j.ymeth.2017.12.010
Publisher site
See Article on Publisher Site

Abstract

•The complex tumor microenvironment is integral to affecting chemotherapeutic response.•Tissue engineering provides a simplified method for interrogating this complexity.•Our model utilizes interstitial flow for physiological chemotherapeutic dosing.•Multiple factors affecting therapeutic response can be assessed via flow cytometry.

Journal

MethodsElsevier

Published: Feb 1, 2018

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve Freelancer

DeepDyve Pro

Price
FREE
$49/month

$360/year
Save searches from
Google Scholar,
PubMed
Create lists to
organize your research
Export lists, citations
Read DeepDyve articles
Abstract access only
Unlimited access to over
18 million full-text articles
Print
20 pages/month
PDF Discount
20% off