Neuropeptide Y (NPY, 1 and 10 pmol), NPY Y 1 receptor agonist (Leu 31 ,Pro 34 )NPY (10 pmol) and Y 2 agonist NPY 13–36 (100 pmol) were administered unilaterally into the region of the nucleus locus coeruleus (LC) in rats. NPY (10 pmol) and NPY 13–36 increased the percentage of open arm entries, the percentage of time spent on open part, number of both open and closed arm entries and line crossings in the open part while (Leu 31 ,Pro 34 )NPY failed to modify elevated plus-maze behavior. These data suggest that NPY applied close to LC has anxiolytic-like effects by acting on NPY Y 2 , not on Y 1 receptors. Thus, NPY Y 2 receptors in the vicinity of LC may be involved in the regulation of anxiety in rats.
Brain Research – Elsevier
Published: Mar 30, 1998
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera