Bioorganic & Medicinal Chemistry Letters 28 (2018) 1050–1055 Contents lists available at ScienceDirect Bioorganic & Medicinal Chemistry Letters journal homepage: www.elsevier.com/locate/bmcl Anti-inﬂammatory isoﬂavones and isoﬂavanones from the roots of Pongamia pinnata (L.) Pierre Ran Wen, Haining Lv, Yong Jiang, Pengfei Tu State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China ar ti c l e i nf o ab stra ct Article history: A phytochemical study on the roots of Pongamia pinnata afforded ﬁve new isoﬂavone and isoﬂavanone Received 14 November 2017 derivatives (1–5), including two previously undescribed phenylisoﬂavones possessing an 1,2-oxetane Revised 30 January 2018 ring, along with 21 known compounds (6–26) among which compound 18 is the ﬁrst time to be isolated Accepted 13 February 2018 from nature. The structures of the isolated compounds were determined on the basis of 1D, 2D NMR, and Available online 15 February 2018 HRESIMS. The absolute conﬁgurations of the compounds were assigned via analysis of the speciﬁc rota- tions and circular dichroism (CD) spectra, as well as by comparison of the calculated and experimental Keywords: electronic circular dichroism (ECD) data. All the isolated compounds were evaluated for their inhibitory Pongamia pinnata effects on
Bioorganic & Medicinal Chemistry Letters – Elsevier
Published: Apr 1, 2018
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.
All for just $49/month
Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.
Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.
It’s easy to organize your research with our built-in tools.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera