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maintenance therapy prevents tumor regrowth after fractionated irradiation of murine tumor models. Cancer Res . 2003 ; 63 : 4009 -4016. 27 Faivre S, Delbaldo C, Vera K, et al. Safety, pharmacokinetic ...
, and evaluate serial biopsies for markers of response to therapy in patients with locally recurrent or chemotherapy-refractory, locally advanced breast cancer . Tumor biopsy samples were obtained at three time ...
intraperitoneal doxorubicin. Sugarbaker and colleagues performed a dose escalation study with intraperitoneal doxorubicin using pharmacokinetic monitoring [10, 11]. It was determined that a low total dose (15 mg/m2 ...
in this study had GEJ tumors [11]. Other options are perioperative chemotherapy based on the MAGIC trial, which included GEJ tumors (11%) [8]. However, GEJ tumors resemble distal esophageal cancers ...
; NWTS, National Wilms’ Tumor Study ; OS: overall survival; RFS : relapse-free survival; SIOP, International Society of Pediatric Oncology; UKW, United Kingdom Children's Cancer Study Group Wilms’ tumor ...
efficacy against xenografts of human squamous cell cancer Tu212, toxicologic studies , pharmacokinetic studies and effects on the NF-κB signaling system by a long term treatment of tumor xenografts. EF31 ...
based chemotherapy for metastatic colorectal cancer (mCRC). We first analysed 1145 miRNAs in 84 colorectal tumors and 5 normal colon mucosae. We then conducted a study with 3 subgroups of patients. Group ...
identify patients in whom tumors are resistant to temozolomide. Author . Path . Study . # Patients . Dose . CR(%) . PR(%) . Remarks . Newlands [19] GBM AA Ph -I Rec 3 200 i.v.; 5/28 d † 0 (0) 2 (67) “Dramatic ...
, Jones SF et al. A phase I and pharmacokinetic study of oral lapatinib administered once or twice daily in patients with solid malignancies Clin Cancer Res 2009 15 6702 – 6708 Google Scholar Crossref ...
, RT. Improved pharmacokinetics and tumor localization of immunotoxins constructed with the Mr 30,000 form of ricin A chain . Cancer Res 1991 ; 51 : 4219 – 25 . Google Scholar PubMed OpenURL Placeholder ...
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