Angiotensin AT1 receptors modulate the anxiogenic effects of angiotensin (5–8) injected into the rat ventrolateral periaqueductal gray

Angiotensin AT1 receptors modulate the anxiogenic effects of angiotensin (5–8) injected into... •Losartan is anxiolytic when injected at high doses into the vlPAG.•Ang (5–8) modulates anxiogenic responses via AT1 receptors (AT1R) into the vlPAG.•AT2-receptor antagonist was not effective in the same paradigm. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Peptides Elsevier

Angiotensin AT1 receptors modulate the anxiogenic effects of angiotensin (5–8) injected into the rat ventrolateral periaqueductal gray

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Publisher
Elsevier
Copyright
Copyright © 2017 Elsevier Ltd
ISSN
0196-9781
D.O.I.
10.1016/j.peptides.2017.08.005
Publisher site
See Article on Publisher Site

Abstract

•Losartan is anxiolytic when injected at high doses into the vlPAG.•Ang (5–8) modulates anxiogenic responses via AT1 receptors (AT1R) into the vlPAG.•AT2-receptor antagonist was not effective in the same paradigm.

Journal

PeptidesElsevier

Published: Oct 1, 2017

References

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