Analytical and clinical performance of the Hologic Aptima HCV Quant Dx Assay for the quantification of HCV RNA in plasma samples

Analytical and clinical performance of the Hologic Aptima HCV Quant Dx Assay for the... •Aptima HCV Quant Dx and CAPCTMv2 HCV tests were highly correlated and inclusive.•The Aptima assay appeared more analytical sensitive than the CAPCTMv2 test.•Linear responses differed with Aptima yielding higher viral loads for HCV-RNA>4.9 Log IU/mL.•Both tests yielded interpretable results when used for monitoring antiviral treatment responses.•Both tests are useful for monitoring patients with HCV infection. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Virological Methods Elsevier

Analytical and clinical performance of the Hologic Aptima HCV Quant Dx Assay for the quantification of HCV RNA in plasma samples

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Publisher
Elsevier
Copyright
Copyright © 2017 Elsevier B.V.
ISSN
0166-0934
eISSN
1879-0984
D.O.I.
10.1016/j.jviromet.2017.07.006
Publisher site
See Article on Publisher Site

Abstract

•Aptima HCV Quant Dx and CAPCTMv2 HCV tests were highly correlated and inclusive.•The Aptima assay appeared more analytical sensitive than the CAPCTMv2 test.•Linear responses differed with Aptima yielding higher viral loads for HCV-RNA>4.9 Log IU/mL.•Both tests yielded interpretable results when used for monitoring antiviral treatment responses.•Both tests are useful for monitoring patients with HCV infection.

Journal

Journal of Virological MethodsElsevier

Published: Oct 1, 2017

References

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