Journal of Photochemistry and Photobiology A: Chemistry 355 (2018) 114–119 Contents lists available at ScienceDirect Journal of Photochemistry and Photobiology A: Chemistry journal home page : www.elsevier.com/locat e/jphotochem Invited feature article An aptamer-based ligation-triggered rolling circle ampliﬁcation strategy for ATP detection and imaging in situ 1 1 * * Fan Wu , Wenting Liu , Shixi Yang, Qian Yao, Yi Chen, Xiaocheng Weng , Xiang Zhou College of Chemistry and Molecular Sciences, Key Laboratory of Biomedical Polymers of Ministry of Education, Wuhan University, Wuhan, Hubei, 430072, PR China A R T I C L E I N F O A B S T R A C T Article history: Adenosine 5 -triphosphate (ATP), one of the most widely known small natural biological molecules, is a Received 26 July 2017 Received in revised form 12 September 2017 multifunctional molecule existing in living organisms and plays an important role in many biological Accepted 30 September 2017 processes. In this work, we have developed an aptamer-based ligation-triggered rolling circle Available online 7 October 2017 ampliﬁcation strategy for ATP detection. Based on ATP aptamer, phosphorylated single oligonucleotide could be speciﬁcally ligated and circularized in the presence of ATP. Then branched rolling circle Keywords:
Journal of Photochemistry and Photobiology A: Chemistry – Elsevier
Published: Mar 15, 2018
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