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of endothelial cells originating in an endothelium and an adjacent 3-D matrix. This strategy provides a new route to the study of anastomosis in vitro , elucidates the role of cellular migration within vascular ...
that can host endothelial cells represent promising tools for the vascularization of engineered tissues. Three-dimensional collagen scaffolds possessing controlled architecture and mechanical stiffness ...
the binding activity of the nanoparticle library against multiple distinct samples of vascular endothelial cells or macrophagesin vitro . We selected primary human endothelial cell isolates derived from a range ...
of angiogenic growth factors and stem/progenitor cells. Vascular endothelial growth factor (VEGF), one of the most well-studied proteins in biomedical science [3], was examined at the turn of the millennium ...
of a collagen matrix seeded with inflammatory breast cancer (IBC) cells around a functional blood vessel to represent the IBC tumor- vascular interface. Over time, the IBC cells secrete pro-angiogenic factors ...
network growth in angiogenesis is initiated when tip cells are selected from endothelial cells (ECs) in pre-existing vasculature in response to biochemical factors, such as vascular endothelial growth ...
. Autologous grafts are the current gold standard of vascular grafting, utilizing the patients’ own veins and arteries as graft conduits. However, not all patients have suitable vessels for autologous grafting ...
is essential for endothelial stabilization through specific binding of vascular growth factors [27]. Open in new tabDownload slide The endothelial basement membrane, composed of laminin and collagen IV strands ...
primary diseases [1–3]. The basement membrane (BM) of vascular endothelial cells is comprised of connective tissue matrix components, including some collagens and laminin [4]. Laminin (LMN ...
. View largeDownload slide Diagrammatic description of the steps involved in angiogenesis. (A) A stable vascular structure comprised of an endothelial monolayer surrounded by mural tissue (ie, basement ...
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