Alkaline pH shock enhanced production of validamycin A in fermentation of Streptomyces hygroscopicus

Alkaline pH shock enhanced production of validamycin A in fermentation of Streptomyces hygroscopicus •A valuable and optimal pH shock strategy for Val-A fermentation was reported.•Alkaline pH shock significantly increased Val-A production by 27.43%.•Respiratory activity and amino acid metabolism were crucial in pH shock treatment.•Effect mechanism based on genes, microenvironments and metabolites was explored. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Bioresource Technology Elsevier

Alkaline pH shock enhanced production of validamycin A in fermentation of Streptomyces hygroscopicus

Loading next page...
 
/lp/elsevier/alkaline-ph-shock-enhanced-production-of-validamycin-a-in-fermentation-psczR3zI09
Publisher
Elsevier
Copyright
Copyright © 2017 Elsevier Ltd
ISSN
0960-8524
D.O.I.
10.1016/j.biortech.2017.10.012
Publisher site
See Article on Publisher Site

Abstract

•A valuable and optimal pH shock strategy for Val-A fermentation was reported.•Alkaline pH shock significantly increased Val-A production by 27.43%.•Respiratory activity and amino acid metabolism were crucial in pH shock treatment.•Effect mechanism based on genes, microenvironments and metabolites was explored.

Journal

Bioresource TechnologyElsevier

Published: Feb 1, 2018

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve Freelancer

DeepDyve Pro

Price
FREE
$49/month

$360/year
Save searches from
Google Scholar,
PubMed
Create lists to
organize your research
Export lists, citations
Read DeepDyve articles
Abstract access only
Unlimited access to over
18 million full-text articles
Print
20 pages/month
PDF Discount
20% off