Age-dependent changes in essential elements and oxidative stress biomarkers in blood of red deer and vulnerability to nutritional deficiencies

Age-dependent changes in essential elements and oxidative stress biomarkers in blood of red deer... Changes in the concentration of circulating essential elements in animals over life may be indicative of periods of vulnerability to deficiencies and associated diseases. Here we studied age-related variations in essential elements (Se, Cu, Zn and Mn) and some selected oxidative stress biomarkers (GPx, SOD, vitamin A and vitamin E) in blood of an Iberian red deer (Cervus elaphus hispanicus) population living in semicaptive conditions. Animals during their first year of life showed to be especially vulnerable to suffer Se- and Cu-related diseases and disorders. Older female deer had lower blood levels of Zn and Mn, which was accompanied by a lower blood SOD activity. On the contrary, GPx blood activity was elevated in older deer, which may help to compensate the reduction of other antioxidants with during aging. Age-related changes in GPx and SOD and their positive relationships with the essential elements suggest that the observed nutritional deficiencies at certain age stages may have a detrimental effect on the antioxidant system, increasing the risk of oxidative stress. Thus, the biomarkers used in the present study may be important tools for the subclinical diagnosis of nutritional disorders and diseases related to the generation of oxidative stress in both domestic and wild ungulates. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Science of the Total Environment Elsevier

Age-dependent changes in essential elements and oxidative stress biomarkers in blood of red deer and vulnerability to nutritional deficiencies

Loading next page...
 
/lp/elsevier/age-dependent-changes-in-essential-elements-and-oxidative-stress-XW03rD1e0A
Publisher
Elsevier
Copyright
Copyright © 2018 Elsevier B.V.
ISSN
0048-9697
eISSN
1879-1026
D.O.I.
10.1016/j.scitotenv.2018.01.072
Publisher site
See Article on Publisher Site

Abstract

Changes in the concentration of circulating essential elements in animals over life may be indicative of periods of vulnerability to deficiencies and associated diseases. Here we studied age-related variations in essential elements (Se, Cu, Zn and Mn) and some selected oxidative stress biomarkers (GPx, SOD, vitamin A and vitamin E) in blood of an Iberian red deer (Cervus elaphus hispanicus) population living in semicaptive conditions. Animals during their first year of life showed to be especially vulnerable to suffer Se- and Cu-related diseases and disorders. Older female deer had lower blood levels of Zn and Mn, which was accompanied by a lower blood SOD activity. On the contrary, GPx blood activity was elevated in older deer, which may help to compensate the reduction of other antioxidants with during aging. Age-related changes in GPx and SOD and their positive relationships with the essential elements suggest that the observed nutritional deficiencies at certain age stages may have a detrimental effect on the antioxidant system, increasing the risk of oxidative stress. Thus, the biomarkers used in the present study may be important tools for the subclinical diagnosis of nutritional disorders and diseases related to the generation of oxidative stress in both domestic and wild ungulates.

Journal

Science of the Total EnvironmentElsevier

Published: Jun 1, 2018

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve Freelancer

DeepDyve Pro

Price
FREE
$49/month

$360/year
Save searches from
Google Scholar,
PubMed
Create lists to
organize your research
Export lists, citations
Read DeepDyve articles
Abstract access only
Unlimited access to over
18 million full-text articles
Print
20 pages/month
PDF Discount
20% off