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to investigate the effect of U-II antagonist on neuropathic pain and to understand the associatedmechanisms. We reported that U-II and its receptor GPR14 were persistently upregulated and activated in the dorsal ...
reveal that the neuronal/astrocytic interaction in the spinal cord by which neuronally produced IL‐36γ activates astrocytes via IL‐36R‐mediated JNK pathway is crucial for the maintenance of chronic ...
was designed to investigate the effect of U-II antagonist on neuropathic pain and to understand the associated mechanisms. We reported that U-II and its receptor GPR14 were persistently upregulated and activated ...
dorsal horn compared to no-PRF group animals (P ...
suggested that JNK activation in spinal cord contributed to the maintenance of CIBP, which may act through modulation of CXCL1. Inhibition of the pJNK/CXCL1 pathway may provide a new choice for treatment ...
by several anticancer agents in erythroleukemia cells. We showed that in treated cells, leflunomide reduced the signalling pathways involved in promoting apoptosis by reducing p38 MAPK and JNK basal activity ...
of oxaprozin on apoptosis of immune complex‐ activated monocytes in comparison with drugs of the same class, and the signalling pathway that leads activated monocytes exposed to oxaprozin to apoptosis ...
Abstract STUDY QUESTION Does P2X ligand-gated ion channel 3 (P2X3) play a role in endometriosis pain ? SUMMARY ANSWER Upregulation of P2X3 in dorsal root ganglia (DRG) tissues via the activating ...
ADS PubMed 16 Gao YJ, Ji RR. Activation of JNK pathway in persistent pain . Neurosci Lett 2008; 437 3: 180– 3. Google Scholar CrossRef Search ADS PubMed 17 Tanga FY, Nutile-McMenemy N, DeLeo JA ...
) continued kratom use despite persistent or recurring social or interpersonal problems caused or made worse by kratom use, (7) stopping or reducing important social, occupational, or recreational activities ...
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