Accelerated reactivity of blood granulocytes in patients with atopic bronchial asthma out of exacerbation

Accelerated reactivity of blood granulocytes in patients with atopic bronchial asthma out of... •Accelerated generation of reactive oxygen species was revealed in the whole blood of patients with bronchial asthma (BA) out of exacerbation.•The kinetics of the response to opsonized zymosan (lag-time, rate and integral) exhibit good discriminative effectiveness for BA individuals.•The test displayed 86% sensitivity and 90% specificity at a linear combination of the parameters.•The primed state of phagocytes was observed in the blood of BA patients out of exacerbation. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Immunobiology Elsevier

Accelerated reactivity of blood granulocytes in patients with atopic bronchial asthma out of exacerbation

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Publisher
Elsevier
Copyright
Copyright © 2017 Elsevier GmbH
ISSN
0171-2985
eISSN
1878-3279
D.O.I.
10.1016/j.imbio.2017.10.020
Publisher site
See Article on Publisher Site

Abstract

•Accelerated generation of reactive oxygen species was revealed in the whole blood of patients with bronchial asthma (BA) out of exacerbation.•The kinetics of the response to opsonized zymosan (lag-time, rate and integral) exhibit good discriminative effectiveness for BA individuals.•The test displayed 86% sensitivity and 90% specificity at a linear combination of the parameters.•The primed state of phagocytes was observed in the blood of BA patients out of exacerbation.

Journal

ImmunobiologyElsevier

Published: Jan 1, 2018

References

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