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Introduction Fusion between HIV-1 virions and target cells engenders the release of the viral capsid into the host cell cytoplasm. The capsid , a cone-shaped protein assembly composed of approximately ...
to form viral -like capsids , as it forms large capsids that encapsulate RNA to transfer it between neurons, or, as shown in Drosophila, from neuron to muscle [17,20]. Arc preferably forms these assemblies ...
core binding, TRIM5α induces accelerated capsid dissociation or uncoating, inhibits reverse transcription, and activates innate immune signaling pathways [1, 3, 4]. Like other members of the TRIM family ...
of poliomyelitis [1]. The icosahedral capsid of the virus, which is made of four proteins, namely VP1, VP2, VP3, and VP4, encloses the viral genome [2]. The capsid is structurally similar to other members ...
that can bind dsRNA, the viral outer- capsid protein, σ3 [16]. Overexpression of wild-type (WT) σ3, but not a dsRNA-binding-deficient mutant of σ3, rescues the inhibition of translation induced by PKR ...
, there is current evidence suggesting that cutaneous HPVs could act through a “hit-and-run” mechanism in which viral oncogene expression plays a role in initiation of transformation but is ultimately no longer ...
smaller proteins required for replication of the viral RNA and capsid assembly. Processing of the P1 precursor by the viral proteases 3Cpro/3CDpro yields the capsid proteins VP0, VP1 and VP3, which remain ...
polysaccharides increases viral thermal stability but it is not known if bacterial polysaccharides affect reovirus stability [38, 42]. To assess the thermostability of reovirus prototypical strains Type 1 Lang (T1L ...
charged DNA to the surface of the micelles thus reducing the intra-/inter-strand DNA repulsion and inducing a coil-to-globule transition . IL also induces efficient compaction of shorter DNA and pDNA. UV ...
bases4a,23 or by interaction with some ligands,24 all of which induce transitions from the B to the A form1 and some of which induce transformation to the Z form.4d In contrast, the RNA double helix adopts ...
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