A review on electrochemical detection of serotonin based on surface modified electrodes

A review on electrochemical detection of serotonin based on surface modified electrodes Serotonin is one of the important neurotransmitters of our body. It’s abnormal concentration is associated with multiple disorders and diseases. Sensitive and precise electrochemical determination of serotonin is not possible with bare working electrodes due to various reasons viz. electro-chemical fouling, presence of other biological molecules having similar oxidation potential, and lower concentration of serotonin in biological samples. Surface modification of working electrode is required for fast, precise, selective, and sensitive detection of serotonin. We have extensively reviewed the research approaches where serotonin has been sensitively detected using surface modified electrodes in the presence of other interfering agents. This review aims at presenting the electrochemical detection of serotonin using various surface modified electrodes such as glassy carbon, graphite, carbon fiber, diamond, screen printed, ITO, and metal electrodes modified with conducting polymers and polyelectrolytes, carbon nanomaterials, metal or metal oxide nanoparticles, biological compounds, and other conducting materials. The analytical figures of merits of various research approaches for detection of serotonin have been compared in the article. The properties of material used for surface modification, chemical interactions at the interfaces, and electrocatalytic effects of modified surfaces on sensing of serotonin have been thoroughly discussed in this review. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Biosensors and Bioelectronics Elsevier

A review on electrochemical detection of serotonin based on surface modified electrodes

Loading next page...
 
/lp/elsevier/a-review-on-electrochemical-detection-of-serotonin-based-on-surface-nDV40K01He
Publisher
Elsevier
Copyright
Copyright © 2018 Elsevier B.V.
ISSN
0956-5663
D.O.I.
10.1016/j.bios.2018.02.013
Publisher site
See Article on Publisher Site

Abstract

Serotonin is one of the important neurotransmitters of our body. It’s abnormal concentration is associated with multiple disorders and diseases. Sensitive and precise electrochemical determination of serotonin is not possible with bare working electrodes due to various reasons viz. electro-chemical fouling, presence of other biological molecules having similar oxidation potential, and lower concentration of serotonin in biological samples. Surface modification of working electrode is required for fast, precise, selective, and sensitive detection of serotonin. We have extensively reviewed the research approaches where serotonin has been sensitively detected using surface modified electrodes in the presence of other interfering agents. This review aims at presenting the electrochemical detection of serotonin using various surface modified electrodes such as glassy carbon, graphite, carbon fiber, diamond, screen printed, ITO, and metal electrodes modified with conducting polymers and polyelectrolytes, carbon nanomaterials, metal or metal oxide nanoparticles, biological compounds, and other conducting materials. The analytical figures of merits of various research approaches for detection of serotonin have been compared in the article. The properties of material used for surface modification, chemical interactions at the interfaces, and electrocatalytic effects of modified surfaces on sensing of serotonin have been thoroughly discussed in this review.

Journal

Biosensors and BioelectronicsElsevier

Published: Jun 1, 2018

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off