A rapid and transient innate immune response to avian influenza infection in mallards

A rapid and transient innate immune response to avian influenza infection in mallards •Mallard ducks (Anas platyrhynchos) are important reservoirs for avian influenza virus (AIV) in nature.•Expression of two innate immune genes in influenza-infected mallards is investigated.•RIG-I and Mx show rapid yet transient upregulation.•The bulk of the immune response is focussed on the first 24 hours of infection.•The spleen plays a key role in the mallard immune response to AIV. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Molecular Immunology Elsevier

A rapid and transient innate immune response to avian influenza infection in mallards

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Publisher
Elsevier
Copyright
Copyright © 2018 Elsevier Ltd
ISSN
0161-5890
D.O.I.
10.1016/j.molimm.2018.01.012
Publisher site
See Article on Publisher Site

Abstract

•Mallard ducks (Anas platyrhynchos) are important reservoirs for avian influenza virus (AIV) in nature.•Expression of two innate immune genes in influenza-infected mallards is investigated.•RIG-I and Mx show rapid yet transient upregulation.•The bulk of the immune response is focussed on the first 24 hours of infection.•The spleen plays a key role in the mallard immune response to AIV.

Journal

Molecular ImmunologyElsevier

Published: Mar 1, 2018

References

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