A novel structural fucosylated chondroitin sulfate from Holothuria Mexicana and its effects on growth factors binding and anticoagulation

A novel structural fucosylated chondroitin sulfate from Holothuria Mexicana and its effects on... •A novel structural FCS was isolated from sea cucumber Holothuria Mexicana.•Four types of branches were found in FCShm with the ratio of 3:4:4:1.•The fucosyl branches of FCShm were α-1,3-linked from dp1 to dp5.•FCShm exhibited high affinity to fibroblast growth factor (FGF)-1 and FGF-2. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Carbohydrate Polymers Elsevier

A novel structural fucosylated chondroitin sulfate from Holothuria Mexicana and its effects on growth factors binding and anticoagulation

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Publisher
Elsevier
Copyright
Copyright © 2017 Elsevier Ltd
ISSN
0144-8617
D.O.I.
10.1016/j.carbpol.2017.10.100
Publisher site
See Article on Publisher Site

Abstract

•A novel structural FCS was isolated from sea cucumber Holothuria Mexicana.•Four types of branches were found in FCShm with the ratio of 3:4:4:1.•The fucosyl branches of FCShm were α-1,3-linked from dp1 to dp5.•FCShm exhibited high affinity to fibroblast growth factor (FGF)-1 and FGF-2.

Journal

Carbohydrate PolymersElsevier

Published: Feb 1, 2018

References

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