A novel fully automated system for quantification of Hepatitis B virus DNA using magnetic bead-based method combined with real-time PCR

A novel fully automated system for quantification of Hepatitis B virus DNA using magnetic... •HBV DNA monitoring plays critical roles in the management of chronic HBV infection.•Highly sensitive and reproducible molecular tests for monitoring HBV DNA level are urgently required in clinic.•Pre-NAT automated platform based on magnetic bead method is harboring higher throughput and automation, with better nucleic acid extraction efficiency.•Pre-NAT HBV DNA quantification assay is comparable to domestic assay and exhibits excellent analytical and clinical performances. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Virological Methods Elsevier

A novel fully automated system for quantification of Hepatitis B virus DNA using magnetic bead-based method combined with real-time PCR

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Publisher
Elsevier
Copyright
Copyright © 2017 Elsevier B.V.
ISSN
0166-0934
eISSN
1879-0984
D.O.I.
10.1016/j.jviromet.2017.07.001
Publisher site
See Article on Publisher Site

Abstract

•HBV DNA monitoring plays critical roles in the management of chronic HBV infection.•Highly sensitive and reproducible molecular tests for monitoring HBV DNA level are urgently required in clinic.•Pre-NAT automated platform based on magnetic bead method is harboring higher throughput and automation, with better nucleic acid extraction efficiency.•Pre-NAT HBV DNA quantification assay is comparable to domestic assay and exhibits excellent analytical and clinical performances.

Journal

Journal of Virological MethodsElsevier

Published: Oct 1, 2017

References

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