50 Years Ago in The Journal of Pediatrics

50 Years Ago in The Journal of Pediatrics March 2018 ORIGINAL ARTICLES 16. Ramírez-Vélez R, Morales O, Peña-Ibagon JC, Palacios-López A, Prieto- weight, height velocity, weight velocity, and stages of puberty. Arch Dis Benavides DH, Vivas A, et al. Normative reference values for handgrip Child 1976;51:170-9. strength in Colombian schoolchildren: the FUPRECOL study. J Strength 21. Hanley JA, McNeil BJ. A method of comparing the areas under receiver Cond Res 2017;31:217-26. operating characteristic curves derived from the same cases. Radiology 17. Ramírez-Vélez R, Rodrigues-Bezerra D, Correa-Bautista JE, Izquierdo M, 1983;148:839-43. Lobelo F. Reliability of health-related physical fitness tests among Co- 22. Sasayama K, Ochi E, Adachi M. Importance of both fatness and aerobic lombian children and adolescents: the FUPRECOL study. PLoS One fitness on metabolic syndrome risk in Japanese children. PLoS One 2015;10:e0140875. 2015;10:e0127400. 18. Zimmet P, Alberti KG, Kaufman F, Tajima N, Silink M, Arslanian S, et al. 23. Welk GJ, Laurson KR, Eisenmann JC, Cureton KJ. Development of youth The metabolic syndrome in children and adolescents: an IDF consensus aerobic-capacity standards using receiver operating characteristic curves. report. Pediatr Diabetes 2007;8:299-306. Am J Prev Med 2011;41(4 Suppl 2):S111-6. 19. de Ferranti SD, Gauvreau K, Ludwig DS, Neufeld EJ, Newburger JW, Rifai 24. Ruiz JR, Cavero-Redondo I, Ortega FB, Welk GJ, Andersen LB, Martinez- N. Prevalence of the metabolic syndrome in American adolescents: find- Vizcaino V. Cardiorespiratory fitness cut points to avoid cardiovascular ings from the Third National Health and Nutrition Examination Survey. disease risk in children and adolescents; what level of fitness should raise Circulation 2004;110:2494-7. a red flag? A systematic review and meta-analysis. Br J Sports Med 20. Tanner JM, Whitehouse RH. Clinical longitudinal standards for height, 2016;50:1451-8. Successful Treatment of Juvenile Hemangiomas with Prednisone Fost NC, Esterly NB. J Pediatr 1968;72:351-7. nfantile hemangioma, the most common infantile soft tissue tumor, has a prevalence of 4%-5%, and although un- I complicated infantile hemangioma can be followed clinically while awaiting involution, up to 15% may be associ- ated with functional impairment, tissue destruction, or permanent disfigurement which necessitates therapy. In 1968, Fost and Esterly reported in The Journal 6 patients with severe infantile hemangioma who were treated with predni- sone, with regression noted in 5. Their patients had complications including ulceration, external auditory canal com- pression, periorbital involvement/proptosis, and subglottic involvement necessitating tracheostomy. Oral prednisone was administered at 20-30 mg daily for 2-16 weeks, and the authors noted marked improvement in 5 patients, with mild growth retardation in one as the only complication. Following up on preliminary observations by Zarem and Edgerton, Fost and Esterly’s findings helped foster the adoption of corticosteroids as first-line treatment for infantile hemangioma. They remained the mainstay of therapy for 4 decades, until the serendipitous discovery in 2008 of propranolol’s effects against infantile hemangioma altered this paradigm. Leaute-Labreze et al reported 2 infants with massive infantile hemangioma treated with propranolol (for cardiac indications) with marked improvement, and 9 others with severe infantile hemangioma who were sub- sequently treated prospectively. A randomized trial of propranolol confirmed its efficacy in infantile hemangioma therapy, and in 2014, the US Food and Drug Administration approved oral propranolol hydrochloride solution for this indi- cation. Propranolol is now considered first-line therapy for complicated infantile hemangioma. This small case series substantiated a relatively well-tolerated and effective treatment for complicated infantile hem- angioma and was a significant contribution to the period literature. Their report, and the recent discovery and vali- dation of propranolol’s effects against infantile hemangioma, remind us of the potential benefits to our patients of academic curiosity, scientific validation, and scholarly dissemination. Anthony J. Mancini,MD Division of Dermatology Ann and Robert H. Lurie Children’s Hospital of Chicago Chicago, Illinois Dr Nancy Esterly passed away on October 8, 2017. She was a giant in the field, often referred to as the “mother of pedi- atric dermatology”, and helped establish our journal, Pediatric Dermatology. The epitome of an academic scholar, savvy clinician, and extraordinary mentor, Dr Esterly’s legacy continues to inspire, and will do so for generations to come. References 1. Zarem HA, Edgerton MT. Induced resolution of cavernous hemangiomas following prednisolone therapy. Plast Reconstr Surg 1967;39:76-83. 2. Leaute-Labreze C, de la Roque ED, Hubiche T, Boralevi F, Thambo JB, Taieb A. Propranolol for severe hemangiomas of infancy. N Engl J Med 2008;358:2649-51. 3. Leaute-Labreze C, Hoeger P, Mazereeuw-Hautier J, Guibaud L, Baselga E, Posiunas G, et al. A randomized, controlled trial of oral propranolol in infantile hemangioma. N Engl J Med 2015;372:735-46. Comparison of Different Maximal Oxygen Uptake Equations to Discriminate the Cardiometabolic Risk in Children and Adolescents http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png The Journal of Pediatrics Elsevier

50 Years Ago in The Journal of Pediatrics

Free
1 page

Loading next page...
1 Page
 
/lp/elsevier/50-years-ago-in-the-journal-of-pediatrics-eyG0Oo6Ylv
Publisher
Elsevier
Copyright
Copyright © 2017 Elsevier Inc.
ISSN
0022-3476
D.O.I.
10.1016/j.jpeds.2017.09.040
Publisher site
See Article on Publisher Site

Abstract

March 2018 ORIGINAL ARTICLES 16. Ramírez-Vélez R, Morales O, Peña-Ibagon JC, Palacios-López A, Prieto- weight, height velocity, weight velocity, and stages of puberty. Arch Dis Benavides DH, Vivas A, et al. Normative reference values for handgrip Child 1976;51:170-9. strength in Colombian schoolchildren: the FUPRECOL study. J Strength 21. Hanley JA, McNeil BJ. A method of comparing the areas under receiver Cond Res 2017;31:217-26. operating characteristic curves derived from the same cases. Radiology 17. Ramírez-Vélez R, Rodrigues-Bezerra D, Correa-Bautista JE, Izquierdo M, 1983;148:839-43. Lobelo F. Reliability of health-related physical fitness tests among Co- 22. Sasayama K, Ochi E, Adachi M. Importance of both fatness and aerobic lombian children and adolescents: the FUPRECOL study. PLoS One fitness on metabolic syndrome risk in Japanese children. PLoS One 2015;10:e0140875. 2015;10:e0127400. 18. Zimmet P, Alberti KG, Kaufman F, Tajima N, Silink M, Arslanian S, et al. 23. Welk GJ, Laurson KR, Eisenmann JC, Cureton KJ. Development of youth The metabolic syndrome in children and adolescents: an IDF consensus aerobic-capacity standards using receiver operating characteristic curves. report. Pediatr Diabetes 2007;8:299-306. Am J Prev Med 2011;41(4 Suppl 2):S111-6. 19. de Ferranti SD, Gauvreau K, Ludwig DS, Neufeld EJ, Newburger JW, Rifai 24. Ruiz JR, Cavero-Redondo I, Ortega FB, Welk GJ, Andersen LB, Martinez- N. Prevalence of the metabolic syndrome in American adolescents: find- Vizcaino V. Cardiorespiratory fitness cut points to avoid cardiovascular ings from the Third National Health and Nutrition Examination Survey. disease risk in children and adolescents; what level of fitness should raise Circulation 2004;110:2494-7. a red flag? A systematic review and meta-analysis. Br J Sports Med 20. Tanner JM, Whitehouse RH. Clinical longitudinal standards for height, 2016;50:1451-8. Successful Treatment of Juvenile Hemangiomas with Prednisone Fost NC, Esterly NB. J Pediatr 1968;72:351-7. nfantile hemangioma, the most common infantile soft tissue tumor, has a prevalence of 4%-5%, and although un- I complicated infantile hemangioma can be followed clinically while awaiting involution, up to 15% may be associ- ated with functional impairment, tissue destruction, or permanent disfigurement which necessitates therapy. In 1968, Fost and Esterly reported in The Journal 6 patients with severe infantile hemangioma who were treated with predni- sone, with regression noted in 5. Their patients had complications including ulceration, external auditory canal com- pression, periorbital involvement/proptosis, and subglottic involvement necessitating tracheostomy. Oral prednisone was administered at 20-30 mg daily for 2-16 weeks, and the authors noted marked improvement in 5 patients, with mild growth retardation in one as the only complication. Following up on preliminary observations by Zarem and Edgerton, Fost and Esterly’s findings helped foster the adoption of corticosteroids as first-line treatment for infantile hemangioma. They remained the mainstay of therapy for 4 decades, until the serendipitous discovery in 2008 of propranolol’s effects against infantile hemangioma altered this paradigm. Leaute-Labreze et al reported 2 infants with massive infantile hemangioma treated with propranolol (for cardiac indications) with marked improvement, and 9 others with severe infantile hemangioma who were sub- sequently treated prospectively. A randomized trial of propranolol confirmed its efficacy in infantile hemangioma therapy, and in 2014, the US Food and Drug Administration approved oral propranolol hydrochloride solution for this indi- cation. Propranolol is now considered first-line therapy for complicated infantile hemangioma. This small case series substantiated a relatively well-tolerated and effective treatment for complicated infantile hem- angioma and was a significant contribution to the period literature. Their report, and the recent discovery and vali- dation of propranolol’s effects against infantile hemangioma, remind us of the potential benefits to our patients of academic curiosity, scientific validation, and scholarly dissemination. Anthony J. Mancini,MD Division of Dermatology Ann and Robert H. Lurie Children’s Hospital of Chicago Chicago, Illinois Dr Nancy Esterly passed away on October 8, 2017. She was a giant in the field, often referred to as the “mother of pedi- atric dermatology”, and helped establish our journal, Pediatric Dermatology. The epitome of an academic scholar, savvy clinician, and extraordinary mentor, Dr Esterly’s legacy continues to inspire, and will do so for generations to come. References 1. Zarem HA, Edgerton MT. Induced resolution of cavernous hemangiomas following prednisolone therapy. Plast Reconstr Surg 1967;39:76-83. 2. Leaute-Labreze C, de la Roque ED, Hubiche T, Boralevi F, Thambo JB, Taieb A. Propranolol for severe hemangiomas of infancy. N Engl J Med 2008;358:2649-51. 3. Leaute-Labreze C, Hoeger P, Mazereeuw-Hautier J, Guibaud L, Baselga E, Posiunas G, et al. A randomized, controlled trial of oral propranolol in infantile hemangioma. N Engl J Med 2015;372:735-46. Comparison of Different Maximal Oxygen Uptake Equations to Discriminate the Cardiometabolic Risk in Children and Adolescents

Journal

The Journal of PediatricsElsevier

Published: Mar 1, 2018

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off