Acta Biomaterialia 71 (2018) 379–387 Contents lists available at ScienceDirect Acta Biomaterialia journal homepage: www.elsevier.com/locate/actabiomat Short communication 3D freeform printing of silk ﬁbroin a a b a Maria J. Rodriguez , Thomas A. Dixon , Eliad Cohen , Wenwen Huang , a a,⇑ Fiorenzo G. Omenetto , David L. Kaplan Department of Biomedical Engineering, Tufts University, Medford, MA, USA Biomedical Engineering Program, University of Massachusetts, Lowell, Lowell, MA, USA article i nfo abstract Article history: Freeform fabrication has emerged as a key direction in printing biologically-relevant materials and struc- Received 23 November 2017 tures. With this emerging technology, complex structures with microscale resolution can be created in Received in revised form 13 February 2018 arbitrary geometries and without the limitations found in traditional bottom-up or top-down additive Accepted 28 February 2018 manufacturing methods. Recent advances in freeform printing have used the physical properties of Available online 15 March 2018 microparticle-based granular gels as a medium for the submerged extrusion of bioinks. However, most of these techniques require post-processing or crosslinking for the removal of the printed structures Keywords: (Miller et al., 2015; Jin et al., 2016) [1,2]. In this communication, we introduce a novel method for the Silk one-step
Acta Biomaterialia – Elsevier
Published: Apr 15, 2018
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