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FA Rivera-Chavez, DL Peters-Hybki, RC Barber, GE O’Keefe (2003)
Interleukin-6 promoter haplotypes and interleukin-6 cytokine responsesShock, 20
(1999)
Report of a WHO Consultation. Part 1: diagnosis and classification of diabetes mellitus
S. Akira, T. Taga, T. Kishimoto (1993)
Interleukin-6 in biology and medicine.Advances in immunology, 54
P. Kern, S. Ranganathan, Chunling Li, Linda Wood, G. Ranganathan (2001)
Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance.American journal of physiology. Endocrinology and metabolism, 280 5
V Mohamed-Ali, S Goodrick, A Rawesh (1997)
Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-alpha in vivoJ Clin Endocrinol Metab, 82
M. Berthier, Ann‐Marie Paradis, A. Tchernof, J. Bergeron, D. Prud'homme, J. Despres, M. Vohl (2003)
The interleukin 6 –174G/C Polymorphism is associated with indices of obesity in menJournal of Human Genetics, 48
Shirley Miller, D. Dykes, H. Polesky (1988)
A simple salting out procedure for extracting DNA from human nucleated cells.Nucleic acids research, 16 3
B. Vozarova, C. Weyer, Kristin Hanson, P. Tataranni, C. Bogardus, R. Pratley (2001)
Circulating interleukin-6 in relation to adiposity, insulin action, and insulin secretion.Obesity research, 9 7
K. Nonogaki, G. Fuller, Nelson Fuentes, A. Moser, I. Staprans, C. Grunfeld, K. Feingold (1995)
Interleukin-6 stimulates hepatic triglyceride secretion in rats.Endocrinology, 136 5
JC Pickup, MB Mattock, GD Chusney, D Burt (1997)
NIDDM as a disease of the innate immune system: association of acute-phase reactants and interleukin-6 with metabolic syndrome XDiabetologia, 40
G. Villuendas, J. Millán, J. Sancho, H. Escobar-Morreale (2002)
The -597 G-->A and -174 G-->C polymorphisms in the promoter of the IL-6 gene are associated with hyperandrogenism.The Journal of clinical endocrinology and metabolism, 87 3
J. Fernández-Real, M. Broch, J. Vendrell, C. Richart, W. Ricart (2000)
Interleukin-6 gene polymorphism and lipid abnormalities in healthy subjects.The Journal of clinical endocrinology and metabolism, 85 3
Journal of Clinical Endocrinology and Metabolism Printed in U.S.A. Copyright © 1997 by The Endocrine Society Subcutaneous Adipose Tissue Releases Interleukin-6, But Not Tumor Necrosis Factor-�, in Vivo*
K. Buetow, Michael Edmonson, Richard Macdonald, R. Clifford, P. Yip, J. Kelley, D. Little, R. Strausberg, H. Koester, Charles Cantor, A. Braun (2001)
High-throughput development and characterization of a genomewide collection of gene-based single nucleotide polymorphism markers by chip-based matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.Proceedings of the National Academy of Sciences of the United States of America, 98 2
T. Jørgensen, K. Borch-Johnsen, T. Thomsen, H. Ibsen, C. Glümer, C. Pisinger (2003)
A randomized non-pharmacological intervention study for prevention of ischaemic heart disease: baseline results Inter99 (1)European Journal of Preventive Cardiology, 10
D. Papanicolaou, R. Wilder, S. Manolagas, G. Chrousos (1998)
The Pathophysiologic Roles of Interleukin-6 in Human DiseaseAnnals of Internal Medicine, 128
C. Terry, V. Loukaci, F. Green (2000)
Cooperative Influence of Genetic Polymorphisms on Interleukin 6 Transcriptional Regulation*The Journal of Biological Chemistry, 275
J. Pickup, G. Chusney, Stephen Thomas, D. Burt (2000)
Plasma interleukin-6, tumour necrosis factor alpha and blood cytokine production in type 2 diabetes.Life sciences, 67 3
A. Kubaszek, J. Pihlajamäki, K. Punnonen, P. Karhapää, I. Vauhkonen, M. Laakso (2003)
The C-174G promoter polymorphism of the IL-6 gene affects energy expenditure and insulin sensitivity.Diabetes, 52 2
B. Vozarova, J. Fernández-Real, W. Knowler, L. Gallart, R. Hanson, Jonathan Gruber, W. Ricart, J. Vendrell, C. Richart, P. Tataranni, J. Wolford (2003)
The interleukin-6 (−174) G/C promoter polymorphism is associated with type-2 diabetes mellitus in Native Americans and CaucasiansHuman Genetics, 112
A. Festa, R. D'Agostino, G. Howard, L. Mykkänen, R. Tracy, S. Haffner (2000)
Chronic subclinical inflammation as part of the insulin resistance syndrome: the Insulin Resistance Atherosclerosis Study (IRAS).Circulation, 102 1
S. Ferrari, L. Ahn-Luong, P. Garnero, S. Humphries, S. Greenspan (2003)
Two promoter polymorphisms regulating interleukin-6 gene expression are associated with circulating levels of C-reactive protein and markers of bone resorption in postmenopausal women.The Journal of clinical endocrinology and metabolism, 88 1
K. Wallenius, J. Jansson, V. Wallenius (2003)
The therapeutic potential of interleukin-6 in treating obesityExpert Opinion on Biological Therapy, 3
T Jorgensen, K Borch-Johnsen, TF Thomsen, H Ibsen, C Glumer, C Pisinger (2003)
A randomized non-pharmacological intervention study for prevention of ischaemic heart disease: baseline results Inter99 (1)Eur J Cardiovasc Prev Rehabil, 10
A. Steensberg, M. Febbraio, T. Osada, P. Schjerling, G. Hall, B. Saltin, B. Pedersen (2001)
Interleukin‐6 production in contracting human skeletal muscle is influenced by pre‐exercise muscle glycogen contentThe Journal of Physiology, 537
Ingrid Wernstedt, A. Eriksson, Anna Berndtsson, J. Hoffstedt, S. Skrtic, T. Hedner, L. Hultén, O. Wiklund, C. Ohlsson, Ja-Hyeon Jo (2004)
A common polymorphism in the interleukin-6 gene promoter is associated with overweightInternational Journal of Obesity, 28
V. Mohamed-ali, L. Flower, Jaswinder Sethi, G. Hotamisligil, R. Gray, S. Humphries, D. York, J. Pinkney (2001)
β-Adrenergic regulation of IL-6 release from adipose tissue: In vivo and in vitro studiesThe Journal of Clinical Endocrinology and Metabolism, 86
J. Senn, P. Klover, I. Nowak, R. Mooney (2002)
Interleukin-6 induces cellular insulin resistance in hepatocytes.Diabetes, 51 12
J. Fernández-Real, M. Vayreda, C. Richart, C. Gutiérrez, M. Broch, J. Vendrell, W. Ricart (2001)
Circulating interleukin 6 levels, blood pressure, and insulin sensitivity in apparently healthy men and women.The Journal of clinical endocrinology and metabolism, 86 3
J. Wolford, Jonathan Gruber, V. Ossowski, B. Vozarova, P. Tataranni, C. Bogardus, R. Hanson (2003)
A C-reactive protein promoter polymorphism is associated with type 2 diabetes mellitus in Pima Indians.Molecular genetics and metabolism, 78 2
J. Fernández-Real, M. Broch, Joan Vendrell, C. Gutiérrez, R. Casamitjana, M. Pugeat, C. Richart, W. Ricart (2000)
Interleukin-6 gene polymorphism and insulin sensitivity.Diabetes, 49 3
Stith Rd, J. Luo (1994)
Endocrine and carbohydrate responses to interleukin-6 in vivo.Circulatory shock, 44 4
K. Rexrode, A. Pradhan, J. Manson, J. Buring, P. Ridker (2003)
Relationship of total and abdominal adiposity with CRP and IL-6 in women.Annals of epidemiology, 13 10
G. Hall, A. Steensberg, M. Sacchetti, C. Fischer, C. Keller, P. Schjerling, N. Hiscock, K. Møller, B. Saltin, M. Febbraio, B. Pedersen (2003)
Interleukin-6 stimulates lipolysis and fat oxidation in humans.The Journal of clinical endocrinology and metabolism, 88 7
M. Müller-Steinhardt, L. Fricke, B. Müller, B. Ebel, H. Kirchner, C. Härtel (2004)
Cooperative Influence of the Interleukin‐6 Promoter Polymorphisms –597, –572 and –174 on Long‐Term Kidney Allograft SurvivalAmerican Journal of Transplantation, 4
C. Tsigos, D. Papanicolaou, I. Kyrou, S. Raptis, G. Chrousos (1999)
Dose-dependent effects of recombinant human interleukin-6 on the pituitary-testicular axis.Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 19 11
G. Gregorio, Lori Hensley, T. Lu, G. Ranganathan, P. Kern (2004)
Lipid and carbohydrate metabolism in mice with a targeted mutation in the IL-6 gene: absence of development of age-related obesity.American journal of physiology. Endocrinology and metabolism, 287 1
FA Rivera-Chavez (2003)
10.1097/00024382-200309000-00004Shock, 20
M. Bonafè, F. Olivieri, L. Cavallone, S. Giovagnetti, F. Marchegiani, M. Cardelli, C. Pieri, M. Marra, R. Antonicelli, R. Lisa, M. Rizzo, G. Paolisso, D. Monti, C. Franceschi (2001)
A gender–dependent genetic predisposition to produce high levels of IL‐6 is detrimental for longevityEuropean Journal of Immunology, 31
V. Wallenius, K. Wallenius, B. Ahrén, M. Rudling, H. Carlsten, S. Dickson, C. Ohlsson, J. Jansson (2002)
Interleukin-6-deficient mice develop mature-onset obesityNature Medicine, 8
P. Martins, E. Kallás, M. Neto, M. Dalboni, S. Blecher, R. Salomão (2003)
Upregulation of Reactive Oxygen Species Generation and Phagocytosis, and Increased Apoptosis in Human Neutrophils During Severe Sepsis and Septic ShockShock, 20
JC Pickup (1997)
10.1007/s001250050822Diabetologia, 40
M. Boulanger, D. Chow, E. Brevnova, K. Garcia (2003)
Hexameric Structure and Assembly of the Interleukin-6/IL-6 α-Receptor/gp130 ComplexScience, 300
F. Olivieri, M. Bonafè, L. Cavallone, S. Giovagnetti, F. Marchegiani, M. Cardelli, Elena Mugianesi, C. Giampieri, R. Moresi, R. Stecconi, R. Lisa, C. Franceschi (2002)
The −174 C/G locus affects in vitro/in vivo IL-6 production during agingExperimental Gerontology, 37
A. Pradhan, J. Manson, N. Rifai, Julie Buring, P. Ridker (2001)
C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus.JAMA, 286 3
A. Kitamura, G. Hasegawa, H. Obayashi, K. Kamiuchi, M. Ishii, M. Yano, T. Tanaka, M. Yamaguchi, H. Shigeta, M. Ogata, N. Nakamura, Toshikazu Yoshikawa (2002)
Interleukin‐6 polymorphism (–634C/G) in the promotor region and the progression of diabetic nephropathy in Type 2 diabetesDiabetic Medicine, 19
D. Fishman, G. Faulds, R. Jeffery, V. Mohamed-ali, J. Yudkin, S. Humphries, P. Woo (1998)
The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis.The Journal of clinical investigation, 102 7
The present studies suggest that single-nucleotide polymorphisms and composite genotypes or haplotypes of the IL6 promoter may be associated with several features of the metabolic syndrome in Caucasians.
Diabetologia – Springer Journals
Published: Feb 1, 2005
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