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Safety of Virus-Resistant Transgenic Plants Two Decades After Their Introduction: Lessons from Realistic Field Risk Assessment Studies *

Safety of Virus-Resistant Transgenic Plants Two Decades After Their Introduction: Lessons from... Abstract Potential safety issues have been raised with the development and release of virus-resistant transgenic plants. This review focuses on safety assessment with a special emphasis on crops that have been commercialized or extensively tested in the field such as squash, papaya, plum, grape, and sugar beet. We discuss topics commonly perceived to be of concern to the environment and to human health—heteroencapsidation, recombination, synergism, gene flow, impact on nontarget organisms, and food safety in terms of allergenicity. The wealth of field observations and experimental data is critically evaluated to draw inferences on the most relevant issues. We also express inside views on the safety and benefits of virus-resistant transgenic plants, and recommend realistic risk assessment approaches to assist their timely deregulation and release. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annual Review of Phytopathology Annual Reviews

Safety of Virus-Resistant Transgenic Plants Two Decades After Their Introduction: Lessons from Realistic Field Risk Assessment Studies *

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Publisher
Annual Reviews
Copyright
Copyright © 2007 by Annual Reviews. All rights reserved
ISSN
0066-4286
eISSN
1545-2107
DOI
10.1146/annurev.phyto.45.062806.094434
pmid
17408355
Publisher site
See Article on Publisher Site

Abstract

Abstract Potential safety issues have been raised with the development and release of virus-resistant transgenic plants. This review focuses on safety assessment with a special emphasis on crops that have been commercialized or extensively tested in the field such as squash, papaya, plum, grape, and sugar beet. We discuss topics commonly perceived to be of concern to the environment and to human health—heteroencapsidation, recombination, synergism, gene flow, impact on nontarget organisms, and food safety in terms of allergenicity. The wealth of field observations and experimental data is critically evaluated to draw inferences on the most relevant issues. We also express inside views on the safety and benefits of virus-resistant transgenic plants, and recommend realistic risk assessment approaches to assist their timely deregulation and release.

Journal

Annual Review of PhytopathologyAnnual Reviews

Published: Sep 8, 2007

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