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Endurance run increases circulating IL-6 and IL-1ra but downregulates ex vivo TNF-alpha and IL-1 beta production

Endurance run increases circulating IL-6 and IL-1ra but downregulates ex vivo TNF-alpha and IL-1... of IL-lp, IL-6, TNF-cr, IL-lra ex vivo production (using a whole blood culture system) of IL-lp, TNF-cw, IL-lra. MATERIALSMETHODS Exercise protocol human subjects. A total of 73 athletes (71 men 2 women) entered a 6-h competition on October 16,1994, in Geldrop, The Netherls. Thirty participants were asked by telephone, in the weeks before the , to join the proposed study. Finally, 21 well-trained long-distance male athletes (mean age 43.7 t 8.4 yr, range 26-59 yr) participated in our study. These volunteers are regularly involved in long-distance ning competitions. The ambient temperature at that day was 12’C, with a humidity of 70%. The wind velocity was 5.5 m/s. After explanation of the aims of the study, written informed consent was obtained from all participants. The participants refrained from exercise in the 24-h period before the first test. The study was approved by the Ethical Committee of the St. Joseph Hospital in Veldhoven, The Netherls. Blood samples. Blood samples were drawn from the antecubital vein at rest in a sitting position 24 h before the projected end of the (to correct as much as possible for circadian effects) immediately after end of the exercise. Blood for cytokine measurements was collected http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Applied Physiology The American Physiological Society

Endurance run increases circulating IL-6 and IL-1ra but downregulates ex vivo TNF-alpha and IL-1 beta production

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Publisher
The American Physiological Society
Copyright
Copyright © 1995 the American Physiological Society
ISSN
8750-7587
eISSN
1522-1601
Publisher site
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Abstract

of IL-lp, IL-6, TNF-cr, IL-lra ex vivo production (using a whole blood culture system) of IL-lp, TNF-cw, IL-lra. MATERIALSMETHODS Exercise protocol human subjects. A total of 73 athletes (71 men 2 women) entered a 6-h competition on October 16,1994, in Geldrop, The Netherls. Thirty participants were asked by telephone, in the weeks before the , to join the proposed study. Finally, 21 well-trained long-distance male athletes (mean age 43.7 t 8.4 yr, range 26-59 yr) participated in our study. These volunteers are regularly involved in long-distance ning competitions. The ambient temperature at that day was 12’C, with a humidity of 70%. The wind velocity was 5.5 m/s. After explanation of the aims of the study, written informed consent was obtained from all participants. The participants refrained from exercise in the 24-h period before the first test. The study was approved by the Ethical Committee of the St. Joseph Hospital in Veldhoven, The Netherls. Blood samples. Blood samples were drawn from the antecubital vein at rest in a sitting position 24 h before the projected end of the (to correct as much as possible for circadian effects) immediately after end of the exercise. Blood for cytokine measurements was collected

Journal

Journal of Applied Physiology – The American Physiological Society

Published: Nov 1, 1995

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