Access the full text.
Sign up today, get DeepDyve free for 14 days.
H. Jia, T. Damush, Haijing Qin, L. Ried, Xinping Wang, L. Young, Linda Williams (2006)
The Impact of Poststroke Depression on Healthcare Use by Veterans With Acute StrokeStroke, 37
T. Craft, A. Devries (2006)
Role of IL-1 in Poststroke Depressive-like Behavior in MiceBiological Psychiatry, 60
John, R. Lipsey, Godfrey, D., Pearlson, Robert, G., Robinson, Krishna Rao, Thomas, R. Price (2003)
POST-STROKE DEPRESSION : A DOUBLE-BLIND STUDY
(1996)
therapy of the post-stroke depression
(2005)
predictors of poststroke depression
R. Robinson, L. Starr, K. Kubos, T. Price (1983)
A two‐year longitudinal study of post‐stroke mood disorders: findings during the initial evaluation.Stroke, 14
S. Fruehwald, E. Gatterbauer, P. Rehak, U. Baumhackl (2003)
Early fluoxetine treatment of post-stroke depressionJournal of Neurology, 250
K. Narushima, J. Kosier, R. Robinson (2003)
A reappraisal of poststroke depression, intra- and inter-hemispheric lesion location using meta-analysis.The Journal of neuropsychiatry and clinical neurosciences, 15 4
A. Rasmussen, M. Lunde, K. Sorensen, S. Qvitzau, P. Bech (2002)
A double-blind placebo-controlled study of sertraline in the prevention of depression in stroke patientsEuropean Neuropsychopharmacology, 12
(2000)
depression : a double - blind placebo - controlled study
Sushmita Ghose, L. Williams, R. Swindle (2005)
Depression and Other Mental Health Diagnoses After Stroke Increase Inpatient and Outpatient Medical Utilization Three Years PoststrokeMedical Care, 43
M. Kimura, K. Kanetani, R. Imai, H. Suzuki, K. Isayama, S. Endo (2002)
Therapeutic effects of milnacipran, a serotonin and noradrenaline reuptake inhibitor, on post-stroke depressionInternational Clinical Psychopharmacology, 17
(2002)
miology, pathophysiology, and biological treatment
L. Rampello, S. Chiechio, G. Nicoletti, A. Alvano, I. Vecchio, R. Raffaele, M. Malaguarnera (2004)
Prediction of the response to citalopram and reboxetine in post-stroke depressed patientsPsychopharmacology, 173
G. Andersen, K. Vestergaard, L. Lauritzen (1994)
Effective Treatment of Poststroke Depression With the Selective Serotonin Reuptake Inhibitor CitalopramStroke, 25
Charles Grade, Becky Redford, Jay Chrostowski, L. Toussaint, Barry Blackwell (1998)
Methylphenidate in early poststroke recovery: a double-blind, placebo-controlled study.Archives of physical medicine and rehabilitation, 79 9
J. Collie
Malingering in Accident and DiseaseThe Lancet, 1
Prevalence of depression and use of antidepressant medication at 5 - years
(1996)
hemiplegic patients undergoing rehabilitation therapy
A. Carson, S. Machale, K. Allen, S. Lawrie, M. Dennis, A. House, M. Sharpe (2000)
Depression after stroke and lesion location: a systematic reviewThe Lancet, 356
M. Dam, P. Tonin, A. Boni, G. Pizzolato, S. Casson, M. Ermani, U. Freo, L. Piron, L. Battistin (1996)
Effects of fluoxetine and maprotiline on functional recovery in poststroke hemiplegic patients undergoing rehabilitation therapy.Stroke, 27 7
Seana Paul, H. Dewey, J. Sturm, R. Macdonell, A. Thrift (2006)
Prevalence of Depression and Use of Antidepressant Medication at 5-Years Poststroke in the North East Melbourne Stroke Incidence StudyStroke, 37
L. Rampello, A. Alvano, S. Chiechio, R. Raffaele, I. Vecchio, M. Malaguarnera (2005)
An evaluation of efficacy and safety of reboxetine in elderly patients affected by "retarded" post-stroke depression. A random, placebo-controlled study.Archives of gerontology and geriatrics, 40 3
R. Robinson (2005)
Vascular depression and poststroke depression: where do we go from here?The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 13 2
R. Ramasubbu, R. Tobias, Alastair Buchan, N. Bech-Hansen (2006)
Serotonin transporter gene promoter region polymorphism associated with poststroke major depression.The Journal of neuropsychiatry and clinical neurosciences, 18 1
N. Niedermaier, E. Bohrer, K. Schulte, P. Schlattmann, I. Heuser (2004)
Prevention and treatment of poststroke depression with mirtazapine in patients with acute stroke.The Journal of clinical psychiatry, 65 12
R. Robinson, S. Schultz, C. Castillo, T. Kopel, Kosier Jt, Newman Rm, K. Curdue, G. Petracca, S. Starkstein (2000)
Nortriptyline versus fluoxetine in the treatment of depression and in short-term recovery after stroke: a placebo-controlled, double-blind study.The American journal of psychiatry, 157 3
H. Kales, D. Maixner, A. Mellow (2005)
Cerebrovascular disease and late-life depression.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 13 2
R. Vataja, T. Pohjasvaara, R. Mäntylä, R. Ylikoski, Maarit Leskelä, H. Kalska, M. Hietanen, Hannu Aronen, O. Salonen, M. Kaste, A. Leppävuori, T. Erkinjuntti (2005)
Depression-executive dysfunction syndrome in stroke patients.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 13 2
S. Dieguez, F. Staub, L. Bruggimann, J. Bogousslavsky (2004)
Is poststroke depression a vascular depression?Journal of the Neurological Sciences, 226
T. Pohjasvaara, A. Leppävuori, Irina Siira, R. Vataja, Markku Kaste, T. Erkinjuntti (1998)
Frequency and clinical determinants of poststroke depression.Stroke, 29 11
M. Reding, L. Orto, Steven Winter, Ilia, M. Fortuna, Pompeo Ponte, F. Mcdowell (1986)
Antidepressant therapy after stroke. A double-blind trial.Archives of neurology, 43 8
R. Jorge, R. Robinson, Stephan Arndt, S. Starkstein (2003)
Mortality and poststroke depression: a placebo-controlled trial of antidepressants.The American journal of psychiatry, 160 10
S. Bhogal, R. Teasell, N. Foley, M. Speechley (2005)
Heterocyclics and Selective Serotonin Reuptake Inhibitors in the Treatment and Prevention of Poststroke DepressionJournal of the American Geriatrics Society, 53
(2006)
stroke: results from a randomized placebo-controlled trial
H. Palomäki, M. Kaste, Anu Berg, Riitta Lönnqvist, J. Lönnqvist, M. Lehtihalmes, Juhani Hares (1999)
Prevention of poststroke depression: 1 year randomised placebo controlled double blind trial of mianserin with 6 month follow up after therapyJournal of Neurology, Neurosurgery & Psychiatry, 66
V. Murray, M. Arbin, A. Bartfai, A-L Berggren, A. Landtblom, J. Lundmark, P. Näsman, J. Olsson, M. Samuelsson, A. Térent, R. Varelius, M. Åsberg, B. Mårtensson (2005)
Double-blind comparison of sertraline and placebo in stroke patients with minor depression and less severe major depression.The Journal of clinical psychiatry, 66 6
(2006)
Role of IL-1 in poststroke depressivelike behavior in mice
V. Bozikas, G. Gold, E. Kövari, F. Herrmann, A. Karavatos, P. Giannakopoulos, C. Bouras (2005)
Pathological correlates of poststroke depression in elderly patients.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 13 2
(2002)
milnacipran, a serotonin and noradrenaline reuptake inhibitor, on post-stroke depression
L. Williams, Sushmita Ghose, R. Swindle (2004)
Depression and other mental health diagnoses increase mortality risk after ischemic stroke.The American journal of psychiatry, 161 6
J. Roh, Ki-Hyoung Lee, Manho Kim, Minoru Yamamoto (1996)
ACCELERATED RECOVERY FROM ISCHEMIC STROKE WITH INDELOXAZINE HYDROCHLORIDE: RESULTS OF A DOUBLE-MASKED CLINICAL STUDY IN KOREACurrent Therapeutic Research-clinical and Experimental, 57
A. Carota, A. Berney, S. Aybek, G. Iaria, F. Staub, F. Ghika-Schmid, L. Annable, P. Guex, J. Bogousslavsky (2005)
A prospective study of predictors of poststroke depressionNeurology, 64
M. Ouimet, F. Primeau, MG Cole (2001)
Psychosocial Risk Factors in Poststroke Depression: A Systematic ReviewThe Canadian Journal of Psychiatry, 46
(1986)
therapy after stroke. A double-blind trial
A. Rasmussen, M. Lunde, D. Poulsen, K. Sørensen, S. Qvitzau, P. Bech (2003)
A double-blind, placebo-controlled study of sertraline in the prevention of depression in stroke patients.Psychosomatics, 44 3
J. Gaete, J. Bogousslavsky (2008)
Post-stroke depressionExpert Review of Neurotherapeutics, 8
(1984)
Nortriptyline treatment of poststroke depression: a double-blind study
L. Wiart, H. Petit, P. Joseph, J. Mazaux, M. Barat (2000)
Fluoxetine in early poststroke depression: a double-blind placebo-controlled study.Stroke, 31 8
G. Spalletta, A. Ripa, C. Caltagirone (2005)
Symptom profile of DSM-IV major and minor depressive disorders in first-ever stroke patients.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 13 2
(2005)
Mellow AM: Cerebrovascular disease and late-life depression
(2004)
other mental health diagnoses increase mortality risk after ischemic stroke
G. Spalletta, P. Bossù, A. Ciaramella, P. Bria, C. Caltagirone, R. Robinson (2006)
The etiology of poststroke depression: a review of the literature and a new hypothesis involving inflammatory cytokinesMolecular Psychiatry, 11
J. Kosier, Robert Robinson (2002)
Preventing Poststroke Depression: A 12-Week Double-Blind Randomized Treatment Trial and 21-Month Follow-upThe Journal of Nervous and Mental Disease, 190
N. Dahmen, J. Marx, H. Hopf, B. Tettenborn, R. Röder (1999)
Therapy of early poststroke depression with venlafaxine: safety, tolerability, and efficacy as determined in an open, uncontrolled clinical trial.Stroke, 30 3
R. Robinson, L. Starr, J. Lipsey, Krishna Rao, T. Price (1984)
A Two-Year Longitudinal Study of Post-Stroke Mood Disorders: Dynamic Changes in Associated Variables Over the First Six Months of Follow-UpStroke, 15
J. Rabe‐Jabłońska (1993)
[Affective disorders in the fourth edition of the classification of mental disorders prepared by the American Psychiatric Association -- diagnostic and statistical manual of mental disorders].Psychiatria polska, 27 3
O. Almeida, A. Waterreus, G. Hankey (2006)
Preventing depression after stroke: Results from a randomized placebo-controlled trial.The Journal of clinical psychiatry, 67 7
R. Raffaele, L. Rampello, I. Vecchio, C. Tornali, M. Malaguarnera (1996)
Trazodone therapy of the post-stroke depression.Archives of gerontology and geriatrics, 22 Suppl 1
Ellen Whyte, B. Mulsant (2002)
Post stroke depression: epidemiology, pathophysiology, and biological treatmentBiological Psychiatry, 52
S. Fruehwald, E. Gatterbauer, P. Rehak, U. Baumhackl (2003)
Early fluoxetine treatment of post-stroke depression--a three-month double-blind placebo-controlled study with an open-label long-term follow up.Journal of neurology, 250 3
(1984)
mood disorders : dynamic changes in associated variables over the first six months of follow - up
T. Lempert, A. Malek, V. Halbach, C. Phatouros, C. Dowd, R. Higashida (1999)
Therapy of Early Poststroke Depression With Venlafaxine: Safety, Tolerability, and Efficacy as Determined in an Open, Uncontrolled Clinical Trial
(1994)
Post-stroke depression: combined treatment with imipramine or desipramine and mianserin. A controlled clinical study
(2003)
fluoxetine treatment of post-stroke depression: a three-month double-blind placebo-controlled study with an open-label long-term follow up
This is a nice review on the pathophysiology of vascular depression and PSD
(1995)
Diagnostic and Statistical Manual of Mental Disorders
Depression is the most common psychiatric complication after stroke. Its prevalence varies from 20% to 80%, and it is underdiagnosed and undertreated. It has significant impact on rehabilitation, motor recovery, activities of daily living, social and interpersonal life, and mortality. Several studies have shown that biological and psychosocial factors play significant roles in the development of this disabling disease. Recent research shows that neurochemical processes also may play some role in the pathophysiology of this condition. Several trials have shown evidence that the older, as well as newer antidepressants and psychostimulants may reduce/prevent depressive symptoms after stroke. At this point there are no clear guidelines available to choose safe and effective treatments. Drugs are selected based on their efficacy and side effect profile in these patients. More research is needed to understand the pathophysiology of depression after stroke. There also is a need for more randomized clinical trials to better treat patients with this condition.
Current Psychiatry Reports – Springer Journals
Published: Jul 3, 2007
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.