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During the past several years, significant advances have occurred in our understanding of the role of selenium in human nutrition and health. This is due in part to the discovery of naturally occurring human selenium deficienc ies in some areas of the world.In certain other selenium-poor regions, studies on the metabolism and nutritional bioavailability of selenium have been facilitated by the low selenium status of the populations living there. As a result, research in the selenium field has rapidly acquired an international flavor. The purpose of this review is to provide the reader with a global view of ongoing and recent work concerning the role of selenium in human nutrition and health. Previous reviews in this series have covered the biochemistry (23) and physiological effects of selenium in animals (9). EVIDENCE FOR WORLDWIDE DIFFERENCES IN SELENIUM STATUS Dietary Selenium Intakes Selenium is efficiently transferred up the soil-plant-animal-human food chain so that geographical differences in the availability of the selenium in soil for uptake by plants account for most variations in the selenium content of foods (54). Estimates of adult daily dietary selenium intakes worldwide range over more than three orders of magnitude. The most extreme values have been
Annual Review of Nutrition – Annual Reviews
Published: Jul 1, 1987
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