Access the full text.
Sign up today, get DeepDyve free for 14 days.
Loading next page...
/lp/rockefeller-university-press/the-preparation-and-function-of-the-hypertensin-converting-enzyme-w8qYRIfVAS
References (10)
-
(1953)
em .rupss.org D ow nladed fom -
Skeggs Lt, Kahn, Marsh Wh (1953)
A method of assaying small amounts of hypertensin.Laboratory investigation; a journal of technical methods and pathology, 2 2
-
(1955)
A factor in plasma that enhances contraction produced by angiotonin on rabbit aortic strips, Fed -
L. Skeggs, W. Marsh, J. Kahn, N. Shumway (1955)
AMINO ACID COMPOSITION AND ELECTROPHORETIC PROPERTIES OF HYPERTENSIN IThe Journal of Experimental Medicine, 102
-
J. Quastel (1944)
Chemistry and Methods of EnzymesNature, 154
-
L. Skeggs, W. Marsh, J. Kahn, N. Shumway (1954)
THE EXISTENCE OF TWO FORMS OF HYPERTENSINThe Journal of Experimental Medicine, 99
-
L. Skeggs, W. Marsh, J. Kahn, N. Shumway (1954)
THE PURIFICATION OF HYPERTENSIN IThe Journal of Experimental Medicine, 100
-
L. Skeggs, J. Leonards, C. Heisler (1949)
Artificial Kidney. II. Construction and Operation of an Improved Continuous Dialyzer.∗Proceedings of the Society for Experimental Biology and Medicine, 72
-
S. Moore, W. Stein (1954)
A modified ninhydrin reagent for the photometric determination of amino acids and related compounds.The Journal of biological chemistry, 211 2
-
H. Goldblatt (1947)
The renal origin of hypertension.Physiological reviews, 27 1
- Publisher
- Rockefeller University Press
- Copyright
- © 1956 Rockefeller University Press
- ISSN
- 0022-1007
- eISSN
- 1540-9538
- DOI
- 10.1084/jem.103.3.295
- Publisher site
- See Article on Publisher Site
Abstract
It has been shown by use of isolated, perfused rat kidneys that hypertensin II is a potent vasoconstrictor substance while hypertensin I is not. Hence it would appear that in intact animals the pressor activity of hypertensin I results from its rapid conversion to hypertensin II. An enzyme which effects this conversion has been procured from horse plasma in a semipurified form by means of ammonium sulfate fractionation and isoelectric precipitation. A method is described for estimating the activity of the enzyme. An example of the use of the preparation in converting purified hypertensin I to hypertensin II has been described. Footnotes Submitted: 13 November 1955
Journal
The Journal of Experimental Medicine – Rockefeller University Press
Published: Mar 1, 1956