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J. Scheinman, A. Fish, A. Matas, A. Michael (1978)
The immunohistopathology of glomerular antigens. II. The glomerular basement membrane, actomyosin, and fibroblast surface antigens in normal, diseased, and transplanted human kidneys.The American journal of pathology, 90 1
E. Engvall, E. Ruoslahti, E. Miller (1978)
Affinity of fibronectin to collagens of different genetic types and to fibrinogenThe Journal of Experimental Medicine, 147
K. Hedman, A. Vaheri, J. Wartiovaara (1978)
External fibronectin of cultured human fibroblasts is predominantly a matrix proteinThe Journal of Cell Biology, 76
M. Perkins, T. Ji, Richard Hynest (1979)
Cross-linking of fibronectin to sulfated proteoglycans at the cell surfaceCell, 16
Kenneth Yamada, K. Olden (1978)
Fibronectins—adhesive glycoproteins of cell surface and bloodNature, 275
E. Linder, A. Vaheri, E. Ruoslahti, J. Wartiovaara (1975)
Distribution of fibroblast surface antigen in the developing chick embryoThe Journal of Experimental Medicine, 142
R. Timpl, H. Rohde, P. Robey, S. Rennard, J. Foidart, G. Martin (1979)
Laminin--a glycoprotein from basement membranes.The Journal of biological chemistry, 254 19
E. Linder, A. Miettinen, T. Törnroth (1980)
Fibronectin as a marker for the glomerular mesangium in immunohistology of kidney biopsies.Laboratory investigation; a journal of technical methods and pathology, 42 1
I. Singer (1979)
The fibronexus: a transmembrane association of fibronectin-containing fibers and bundles of 5 nm microfilaments in hamster and human fibroblastsCell, 16
E. Macarak, E. Kirby, T. Kirk, N. Kefalides (1978)
Synthesis of cold-insoluble globulin by cultured calf endothelial cells.Proceedings of the National Academy of Sciences of the United States of America, 75 6
Lan Chen, N. Maitland, P. Gallimore, J. Mcdougall (1977)
Detection of the large external transformation-sensitive protein on some epithelial cells.Experimental cell research, 106 1
J. Keski‐oja, D. Mosher, A. Vaheri (1976)
Cross-linking of a major fibroblast surface-associated glycoprotein (fibronectin) catalyzed by blood coagulation factor XIIICell, 9
Yashpal Kanwar, M. Farquhar (1979)
Isolation of glycosaminoglycans (heparan sulfate) from glomerular basement membranes.Proceedings of the National Academy of Sciences of the United States of America, 76 9
L. Culp, B. Rollins, J. Buniel, S. Hitri (1978)
Two functionally distinct pools of glycosaminoglycan in the substrate adhesion site of murine cellsThe Journal of Cell Biology, 79
C. Birdwell, D. Gospodarowicz, G. Nicolson (1978)
Identification, localization, and role of fibronectin in cultured bovine endothelial cells.Proceedings of the National Academy of Sciences of the United States of America, 75 7
R. Graham, M. Karnovsky (1966)
THF EARLY STAGES OF ABSORPTION OF INJECTED HORSERADISH PEROXIDASE IN THE PROXIMAL TUBULES OF MOUSE KIDNEY: ULTRASTRUCTURAL CYTOCHEMISTRY BY A NEW TECHNIQUEJournal of Histochemistry and Cytochemistry, 14
M. Weiss, B. Ooi, Y. Ooi, E. Engvall, E. Ruoslahti (1979)
Immunofluorescent localization of fibronectin in the human kidney.Laboratory investigation; a journal of technical methods and pathology, 41 4
A. Michael (1981)
The glomerular mesangium.Australian and New Zealand journal of medicine, 11 Suppl 1
(1980)
Fibronecti n localization in the rat glomerulus
P. Kuusela, E. Ruoslahti, E. Engvall, A. Vaheri (1976)
Immunological interspecies cross-reactions of fibroblast surface antigen (fibronectin).Immunochemistry, 13 8
(1980)
Receivedfor publication 27 May 1980, and in revisedform 29
E. Pettersson, R. Colvin (1978)
Cold-insoluble globulin (fibronectin, LETS protein) in normal and diseased human glomeruli: papain-sensitive attachment to normal glomeruli and deposition in crescents.Clinical immunology and immunopathology, 11 4
L. Chen, A. Murray, R. Segal, A. Bushnell, M. Walsh (1978)
Studies on intercellular LETS glycoprotein matricesCell, 14
M. Farquhar, G. Palade (1962)
FUNCTIONAL EVIDENCE FOR THE EXISTENCE OF A THIRD CELL TYPE IN THE RENAL GLOMERULUSThe Journal of Cell Biology, 13
(1980)
Comparativ e distribution of fibronectin, type IV collagen, and laminin in the rat glomerulus
Oberley Td, Mosher Df, Mills (1979)
Localization of fibronectin within the renal glomerulus and its production by cultured glomerular cells.The American journal of pathology, 96 3
(1978)
Current status of chemistry and structure of basement membranes
E. Hayman, E. Ruoslahti (1979)
Distribution of fetal bovine serum fibronectin and endogenous rat cell fibronectin in extracellular matrixThe Journal of Cell Biology, 83
S. Stenman, Ann Vaheri (1978)
Distribution of a major connective tissue protein, fibronectin, in normal human tissuesThe Journal of Experimental Medicine, 147
Y. Kanwar, M. Farquhar (1980)
Detachment of endothelium and epithelium from the glomerular basement membrane produced by kidney perfusion with neuraminidase.Laboratory investigation; a journal of technical methods and pathology, 42 3
K. Yamada, D. Kennedy (1979)
Fibroblast cellular and plasma fibronectins are similar but not identicalThe Journal of Cell Biology, 80
1 ., and 1 . Boyles, 1980 . Fibronectin localization in rat capillaries
M. Siperstein, A. Colwell, K. Mayer (1964)
Small blood vessel involvement in diabetes mellitus
V. Mautner, R. Hynes (1977)
Surface distribution of LETS protein in relation to the cytoskeleton of normal and transformed cellsThe Journal of Cell Biology, 75
Yashpal Kanwar, M. Farquhar (1979)
Anionic sites in the glomerular basement membrane. In vivo and in vitro localization to the laminae rarae by cationic probesThe Journal of Cell Biology, 81
L. Furcht, D. Mosher, G. Wendelschafer‐Crabb (1978)
Immunocytochemical localization of fibronectin (LETS protein) on the surface of L6 myoblasts: light and electron microscopic studiesCell, 13
R. Hynes, A. Destree (1978)
Relationships between fibronectin (LETS protein) and actinCell, 15
(1964)
Glomerular permeability investigated by electron microscopy
Fibronectin (FN) has been localized in the rat glomerulus using indirect immunolabeling. It was demonstrated in frozen sections by immunofluorescence, in sections of fixed kidneys by both peroxidase and ferritin-labeled antibodies, and in isolated glomerular basement membranes (GBM) with ferritin-labeled antibodies. Complementary and convergent results were obtained with these approaches. FN was most abundant in the mesangial matrix where it was especially concentrated at the interface between the endothelial and mesangial cells. In the peripheral capillary loop, FN was also detected in the laminae rarae (interna and externa) of the GBM--i.e., between the endothelial and epithelial cells, respectively, and the GBM. These findings indicate that FN is an important constituent of the glomerulus, and they are compatible with the assumption that, in the glomerulus, as in cultured cells, FN is involved in cell-to-cell (mesangial-mesangial, mesangial-endothelial) and cell-to-substrate (mesangial cell-mesangial matrix, epithelium-GBM, endothelium-GBM) attachment.
The Journal of Cell Biology – Rockefeller University Press
Published: Dec 1, 1980
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