Access the full text.
Sign up today, get DeepDyve free for 14 days.
J. Lehmann (1990)
Neuropeptide Y: An overviewDrug Development Research, 19
K. Backus, T. Berger, H. Kettenmann (1991)
Activation of neurokinin receptors modulates K+ and Cl− channel activity in cultured astrocytes from rat cortexBrain Research, 541
J. Danger, M. Tonon, B. Jenks, S. Saint-Pierre, J. Martel, A. Fasolo, B. Breton, R. Quirion, G. Pelletier, H. Vaudry (1990)
Neuropeptide Y: localization in the central nervous system and neuroendocrine functionsFundamental & Clinical Pharmacology, 4
W. Colmers, Q. Pittman (1989)
Presynaptic inhibition by neuropeptide Y and baclofen in hippocampus: insensitivity to pertussis toxin treatmentBrain Research, 498
M. Walker, D. Ewald, T. Perney, R.J. Miller (1988)
Neuropeptide Y modulates neurotransmitter release and Ca2+ currents in rat sensory neurons, 8
H. Kettenmann (1988)
Electrophysiological Methods Applied in Nervous System Cultures
M. Cleary (1990)
Effect of dehydroepiandrosterone treatment on liver metabolism in rats.The International journal of biochemistry, 22 3
A. Léan, A. Hancock, R. Lefkowitz (1982)
Validation and statistical analysis of a computer modeling method for quantitative analysis of radioligand binding data for mixtures of pharmacological receptor subtypes.Molecular pharmacology, 21 1
Hamill Hamill, Marty Marty, Neher Neher, Sakmann Sakmann, Sigworth Sigworth (1981)
Improved patch‐clamp techniques for high‐resolution current recording from cells and cell‐free membrane patchesPflügers Arch, 391
D. Lynch, M. Walker, R.J. Miller, S. Snyder (1989)
Neuropeptide Y receptor binding sites in rat brain: differential autoradiographic localizations with 125I-peptide YY and 125I- neuropeptide Y imply receptor heterogeneity, 9
K. Tatemoto, M. Carlquist, V. Mutt (1982)
Neuropeptide Y—a novel brain peptide with structural similarities to peptide YY and pancreatic polypeptideNature, 296
T. Perney, Richard Miller (1989)
Two different G-proteins mediate neuropeptide Y and bradykinin-stimulated phospholipid breakdown in cultured rat sensory neurons.The Journal of biological chemistry, 264 13
Lobaugh Lobaugh, Blackshear Blackshear (1990b)
Neuropeptide Y stimulation of myosin light chain phosphorylation in cultured aortic smooth muscle cellsJ Biol Chem, 265
A. Härfstrand, B. Fredholm, K. Fuxe (1987)
Inhibitory effects of neuropeptide Y on cyclic AMP accumulation in slices of the nucleus tractus solitarius region of the ratNeuroscience Letters, 76
(1978)
Some properties of astrocytes
Blankenfeld Blankenfeld, Kettenmann Kettenmann (1992)
Glutamate and GABA receptors in vertebrate glial cellsMol Neurobiol, 5
Y. Nakajima, S. Nakajima, Masumi Inoue (1988)
Pertussis toxin-insensitive G protein mediates substance P-induced inhibition of potassium channels in brain neurons.Proceedings of the National Academy of Sciences of the United States of America, 85 10
J. Hinson, C. Rauh, J. Coupet (1988)
Neuropeptide Y stimulates inositol phospholipid hydrolysis in rat brain miniprismsBrain Research, 446
(1989)
Inhibition of noradrenaline release
M. Heilig, E. Widerlöv (1990)
Neuropeptide Y: an overview of central distribution, functional aspects, and possible involvement in neuropsychiatric illnessesActa Psychiatrica Scandinavica, 82
E. Gordon, T. Kohout, P. Fishman (1990)
Characterization of Functional Neuropeptide Y Receptors in a Human Neuroblastoma Cell LineJournal of Neurochemistry, 55
J. Martel, A. Fournier, S. Pierre, R. Quirion (1990)
Quantitative autoradiographic distribution of [125i]bolton-hunter neuropeptide y receptor binding sites in rat brain. comparison with [125i]peptide yy receptor sitesNeuroscience, 36
P. Casey, H. Fong, Melvin Simon, A. Gilman (1990)
Gz, a guanine nucleotide-binding protein with unique biochemical properties.The Journal of biological chemistry, 265 4
(1988)
A universal data aquisition system for electrophysiology
Brain Electrolytes and Water Spaces
A. Salm, K. McCarthy (1990)
Norepinephrine‐evoked calcium transients in cultured cerebral type 1 astrogliaGlia, 3
Y. Torrens, J. Beaujouan, M. Saffroy, M. Montety, L. Bergström, J. Glowinski (1986)
Substance P receptors in primary cultures of cortical astrocytes from the mouse.Proceedings of the National Academy of Sciences of the United States of America, 83 23
Kirchhoff Kirchhoff, Ohlemeyer Ohlemeyer, Kettenmann Kettenmann (1992)
A fast perfusion system for single cell physiology optimized for microscopes with water immersion objectivesPflügers Arch, 420
K. McCarthy, J. Vellis (1980)
Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissueThe Journal of Cell Biology, 85
G. Gimpl, Jochen Wahl, R. Lang (1991)
Identification of a receptor protein for neuropeptide Y in rabbit kidney G‐protein association and inhibition of adenylate cyclaseFEBS Letters, 279
D. Ewald, Heinrich Matthies, T. Perney, M. Walker, R. Miller (1988)
The effect of down regulation of protein kinase C on the inhibitory modulation of dorsal root ganglion neuron Ca2+ currents by neuropeptide Y, 8
L. Lobaugh, P. Blackshear (1990)
Neuropeptide Y binding and inhibition of cAMP accumulation in human neuroepithelioma cells.The American journal of physiology, 258 5 Pt 1
P. Gierschik, D. Sidiropoulos, A. Spiegel, K. Jakobs (1987)
Purification and immunochemical characterization of the major pertussis-toxin-sensitive guanine-nucleotide-binding protein of bovine-neutrophil membranes.European journal of biochemistry, 165 1
M. Wienrich, H. Kettenmann (1989)
Activation of substance P receptors leads to membrane potential responses in cultured astrocytesGlia, 2
G. Peterson (1977)
A simplification of the protein assay method of Lowry et al. which is more generally applicable.Analytical biochemistry, 83 2
B. MacVicar (1984)
Voltage-dependent calcium channels in glial cells.Science, 226 4680
(1992)
Glutamate and GABA recep
F. Valen, E. Keck, H. Jürgens (1989)
Neuropeptide Y inhibits vasoactive intestinal peptide‐ and dopamine‐induced cyclic AMP formation in human Ewing's sarcoma WE‐68 cellsFEBS Letters, 249
J. Lundberg, L. Terenius, T. Hokfelt, K. Tatemoto (1984)
Comparative immunohistochemical and biochemical analysis of pancreatic polypeptide-like peptides with special reference to presence of neuropeptide Y in central and peripheral neurons, 4
H. Kimelberg (1988)
Glial cell receptors
Foucart Foucart, Majewski Majewski (1989)
Inhibition of noradrenaline release by neuropeptide Y in mouse atria does not involve inhibition of adenylate cyclase or a pertussis toxin‐susceptible G proteinNaunyn Schmiedebergs Arch Pharmacol, 340
S. Mihara, Y. Shigeri, M. Fujimoto (1990)
Neuropeptide Y receptor in cultured vascular smooth muscle cells: ligand binding and increase in cytosolic free Ca2+.Biochemistry international, 22 2
Motulsky Motulsky, Michel Michel (1988)
Neuropeptide Y inhibits adenylate cyclase and mobilize intracellular Ca ++ in human erythroleukemia cellsAm J Physiol, 255
U. Laemmli (1970)
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Nature, 227
Gimpl Gimpl, Wahl Wahl, Lang Lang (1991)
Identification of a receptor protein for neuropeptide Y in rabbit kidneyFEBS Lett, 279
Specific binding sites for neuropeptide Y could be demonstrated in primary cultures of astrocytes from neonatal rat brain. Neuropeptide Y binding was saturable, reversible, and temperature dependent as revealed by saturation studies and kinetic experiments. Scatchard analysis of equilibrium binding data indicated a single population of high‐affinity binding sites with respective KD and Bmax values of 0.43 nM and 6.9 fmol/2.7 × 105 cells. Physiological responses induced by neuropeptide Y could be detected in a distinct subpopulation of cultured astrocytes on the basis of two criteria: (1) electrophysiological responses and (2) single cell measurements of changes in (Ca2+)i. In that fraction of cells responding (20–70%, varying among cultures from different preparations), brief application of neuropeptide Y led to a membrane potential depolarization, lasting several minutes. When the membrane was clamped close to the resting membrane potential using the whole‐cell patch‐clamp technique, neuropeptide Y induced an inward current with a similar time course as the neuropeptide Y‐induced membrane depolarization. As detected by single cell microfluorimetric (fura‐2) measurements neuropeptide Y induced an increase of (Ca2+)i which was caused by the entry of extracellular Ca2+. Both the (Ca2+)i increase and the electrophysiological responses were unaffected by pretreatment of the astrocytes with pertussis toxin. © 1993 Wiley‐Liss, Inc.
Journal of Neuroscience Research – Wiley
Published: Feb 1, 1993
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.