Access the full text.
Sign up today, get DeepDyve free for 14 days.
Loading next page...
/lp/the-american-physiological-society/the-bone-marrow-vascular-niche-home-of-hsc-differentiation-and-s8ZD9nfOus
References
References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.
- Publisher
- The American Physiological Society
- Copyright
- Copyright © 2011 the American Physiological Society
- ISSN
- 1548-9213
- eISSN
- 1548-9221
- DOI
- 10.1152/physiol.00025.2005
- pmid
- 16174874
- Publisher site
- See Article on Publisher Site
Abstract
The bone marrow vasuclar niche consists of a network of thin-walled and fenestrated sinusoidal vessels whose integrity is maintained and supported by surrounding hematopoietic cells. However, this dependence is highly reciprocal in that the bone marrow vasculature provides not only a conduit for mature hematopoietic cells to the peripheral circulation but also a site where hematopoietic progenitors, especially megakaryocytes, differentiate and set the stage for full reconstitution of hematopoiesis.
Journal
Physiology – The American Physiological Society
Published: Oct 1, 2005