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Review article Risk factors for neurodevelopmental outcomes in prematurity An overview of risk factors for poor neurodevelopmental outcome associated with prematurity Tao Xiong, Fernando Gonzalez, De-Zhi Mu Chengdu, China Background: Preterm birth is a major cause of Key words: factor; neonatal mortality and morbidity. While advances in infant; medical care have improved the survival of preterm neurodevelopment; infants, neurodevelopmental problems persist in this outcome; population. This article aims to review factors associated preterm with their neurodevelopmental outcomes. Data sources: English language studies of neurode- velopmental outcomes in preterm infants were retrieved Introduction from PubMed. A total of 100 related publications were reterm birth accounts for 9.6% of all live births included. and is a major cause of neonatal mortality and Results: Early gestational age and birth weight Pmorbidity worldwide. There is a trend toward are the most significant predictors of poor long-term increased morbidity secondary to increased survival of [1,2] neurological outcome. Structural changes of the brain, preterm infants. Complications arising from preterm infection, male gender and neonatal intensive care unit birth are also the leading cause of neonatal and infant [3] course are also important factors affecting eventual mortality worldwide. Given improved survival, outcome. Other complex biological and
World Journal of Pediatrics – Springer Journals
Published: Nov 15, 2012
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