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C. Setoyama, R. Frunzio, G. Liau, M. Mudryj, B. Crombrugghe (1986)
Transcriptional activation encoded by the v-fos gene.Proceedings of the National Academy of Sciences of the United States of America, 83 10
M. Comb, N. Birnberg, A. Seasholtz, E. Herbert, H. Goodman (1986)
A cyclic AMP- and phorbol ester-inducible DNA elementNature, 323
S. Winston, Michael Hayward, E. Nestler, R. Duman (1990)
Chronic Electroconvulsive Seizures Down–Regulate Expression of the Immediate‐Early Genes c‐fos and c‐jun in Rat Cerebral CortexJournal of Neurochemistry, 54
Gundula Risse, Karin Jooss, M. Neuberg, Hans-Joachim Bruller, Rolf Muller (1989)
Asymmetrical recognition of the palindromic AP1 binding site (TRE) by Fos protein complexes.The EMBO Journal, 8
L. Lau, D. Nathans (1985)
Identification of a set of genes expressed during the G0/G1 transition of cultured mouse cells.The EMBO Journal, 4
K. Ryder, A. Lanahan, Evelio Perez-Albuerne, D. Nathans (1989)
jun-D: a third member of the jun gene family.Proceedings of the National Academy of Sciences of the United States of America, 86 5
M. Greenberg, A. Hermanowski, E. Ziff (1986)
Effect of protein synthesis inhibitors on growth factor activation of c-fos, c-myc, and actin gene transcriptionMolecular and Cellular Biology, 6
Y. Maki, T. Bos, C. Davis, M. Starbuck, P. Vogt (1987)
Avian sarcoma virus 17 carries the jun oncogene.Proceedings of the National Academy of Sciences of the United States of America, 84 9
T. Curran, C. Beveren, I. Verma (1985)
Viral and cellular fos proteins are complexed with a 39,000-dalton cellular proteinMolecular and Cellular Biology, 5
B. Cochran, A. Reffel, C. Stiles (1983)
Molecular cloning of gene sequences regulated by platelet-derived growth factorCell, 33
B. Franza, L. Sambucetti, D. Cohen, T. Curran (1987)
Analysis of Fos protein complexes and Fos-related antigens by high-resolution two-dimensional gel electrophoresis.Oncogene, 1 2
A. Curran, Dusty Miller, L. Zokas, I. Verma (1984)
Viral and cellular fos proteins: A comparative analysisCell, 36
D. Hill, I. Hope, J. Macke, K. Struhl (1986)
Saturation mutagenesis of the yeast his3 regulatory site: requirements for transcriptional induction and for binding by GCN4 activator protein.Science, 234 4775
S. Hunt, A. Pini, G. Evan (1987)
Induction of c-fos-like protein in spinal cord neurons following sensory stimulationNature, 328
P. Sassone-Corsi, W. Lamph, M. Kamps, I. Verma (1988)
fos-associated cellular p39 is related to nuclear transcription factor AP-1Cell, 54
M. Montminy, K. Sevarino, John Wagner, G. Mandel, R. Goodman (1986)
Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.Proceedings of the National Academy of Sciences of the United States of America, 83 18
J. Milbrandt (1987)
A nerve growth factor-induced gene encodes a possible transcriptional regulatory factor.Science, 238 4828
L. Lau, D. Nathans (1987)
Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: coordinate regulation with c-fos or c-myc.Proceedings of the National Academy of Sciences of the United States of America, 84 5
J. White, C. Gall (1987)
Differential regulation of neuropeptide and proto-oncogene mRNA content in the hippocampus following recurrent seizures.Brain research, 427 1
L. Ransone, J. Visvader, P. Sassone-Corsi, I. Verma (1989)
Fos-Jun interaction: mutational analysis of the leucine zipper domain of both proteins.Genes & development, 3 6
T. Popovici, G. Barbin, Y. Ari (1988)
Kainic acid-induced seizures increase c-fos-like protein in the hippocampusEuropean Journal of Pharmacology, 150
P. Chavrier, M. Zerial, P. Lemaire, J. Almendral, R. Bravo, P. Charnay (1988)
A gene encoding a protein with zinc fingers is activated during G0/G1 transition in cultured cells.The EMBO Journal, 7
Reiner Gentz, F. Rauscher, C. Abate, T. Curran (1989)
Parallel association of Fos and Jun leucine zippers juxtaposes DNA binding domains.Science, 243 4899
A. Székely, M. Barbaccia, H. Alho, E. Costa (1989)
In primary cultures of cerebellar granule cells the activation of N-methyl-D-aspartate-sensitive glutamate receptors induces c-fos mRNA expression.Molecular pharmacology, 35 4
W. Landschulz, P. Johnson, S. McKnight (1988)
The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins.Science, 240 4860
D. Cohen, T. Curran (1988)
fra-1: a serum-inducible, cellular immediate-early gene that encodes a fos-related antigenMolecular and Cellular Biology, 8
R. Ryseck, H. Macdonald-Bravo, MG Mattei, S. Ruppert, Rodrigo Bravo (1989)
Structure, mapping and expression of a growth factor inducible gene encoding a putative nuclear hormonal binding receptor.The EMBO Journal, 8
M. Dragunow, R. Currie, H. Robertson, R. Faull (1989)
Heat shock induces c-fos protein-like immunoreactivity in glial cells in adult rat brainExperimental Neurology, 106
T. Bos, F. Rauscher, T. Curran, P. Vogt (1989)
The carboxy terminus of the viral Jun oncoprotein is required for complex formation with the cellular Fos protein.Oncogene, 4 2
K. Struhl (1988)
The JUN oncoprotein, a vertebrate transcription factor, activates transcription in yeastNature, 332
T. Mohun, N. Garrett, R. Treisman (1987)
Xenopus cytoskeletal actin and human c‐fos gene promoters share a conserved protein‐binding site.The EMBO Journal, 6
F. Sharp, Manuel Gonzalez, K. Hisanaga, W. Mobley, S. Sagar (1989)
Induction of the c-fos gene product in rat forebrain following cortical lesions and NGF injectionsNeuroscience Letters, 100
S. Sagar, F. Sharp, T. Curran (1988)
Expression of c-fos protein in brain: metabolic mapping at the cellular level.Science, 240 4857
W. Wisden, M. Er̀rington, S. Williams, S. Dunnett, C. Waters, D. Hitchcock, G. Evan, T. Bliss, S. Hunt (1990)
Differential expression of immediate early genes in the hippocampus and spinal cordNeuron, 4
M. Dragunow, H. Robertson (1988)
Brain injury induces c-fos protein(s) in nerve and glial-like cells in adult mammalian brainBrain Research, 455
R. Müller, R. Bravo, J. Burckhardt, T. Curran (1984)
Induction of c-fos gene and protein by growth factors precedes activation of c-mycNature, 312
J. Visvader, P. Sassone-Corsi, I. Verma (1988)
Two adjacent promoter elements mediate nerve growth factor activation of the c-fos gene and bind distinct nuclear complexes.Proceedings of the National Academy of Sciences of the United States of America, 85 24
R. Treisman (1987)
Identification and purification of a polypeptide that binds to the c‐fos serum response element.The EMBO Journal, 6
P. Sassone-Corsi, J. Sisson, I. Verma (1988)
Transcriptional autoregulation of the proto-oncogene fosNature, 334
B. Franza, F. Rauscher, SF Josephs, T. Curran (1988)
The Fos complex and Fos-related antigens recognize sequence elements that contain AP-1 binding sites.Science, 239 4844
Mike Dragunow, Harold Robertson (1987)
Generalized seizures induce c-fos protein(s) in mammalian neuronsNeuroscience Letters, 82
J. Daval, T. Nakajima, C. Gleiter, R. Post, P. Marangos (1989)
Mouse Brain c‐fos mRNA Distribution Following a Single Electroconvulsive ShockJournal of Neurochemistry, 52
D. Saffen, A. Cole, P. Worley, B. Christy, K. Ryder, J. Baraban (1988)
Convulsant-induced increase in transcription factor messenger RNAs in rat brain.Proceedings of the National Academy of Sciences of the United States of America, 85 20
L. Kaczmarek, J. Siedlecki, W. Danysz (1988)
Proto-oncogene c-fos induction in rat hippocampus.Brain research, 427 2
A. Székely, M. Barbaccia, E. Costa (1987)
Activation of specific glutamate receptor subtypes increases c-fos proto-oncogene expression in primary cultures of neonatal rat cerebellar granule cellsNeuropharmacology, 26
L. Joseph, M. Beau, G. Jamieson, S. Acharya, T. Shows, J. Rowley, V. Sukhatme (1988)
Molecular cloning, sequencing, and mapping of EGR2, a human early growth response gene encoding a protein with "zinc-binding finger" structure.Proceedings of the National Academy of Sciences of the United States of America, 85 19
M. Greenberg, L. Greene, E. Ziff (1985)
Nerve growth factor and epidermal growth factor induce rapid transient changes in proto-oncogene transcription in PC12 cells.The Journal of biological chemistry, 260 26
S. Chang, S. Squinto, R. Harlan (1988)
Morphine activation of c-fos expression in rat brain.Biochemical and biophysical research communications, 157 2
J. Morgan, D. Cohen, J. Hempstead, T. Curran (1987)
Mapping patterns of c-fos expression in the central nervous system after seizure.Science, 237 4811
R. Distel, H. Ro, B. Rosen, D. Groves, B. Spiegelman (1987)
Nucleoprotein complexes that regulate gene expression in adipocyte differentiation: direct participation of c-fosCell, 49
M. Matsui, M. Tokuhara, Y. Konuma, N. Nomura, R. Ishizaki (1990)
Isolation of human fos-related genes and their expression during monocyte-macrophage differentiation.Oncogene, 5 3
Y. Nakabeppu, K. Ryder, D. Nathans (1988)
DNA binding activities of three murine Jun proteins: Stimulation by FosCell, 55
L. Sambucetti, T. Curran (1986)
The Fos protein complex is associated with DNA in isolated nuclei and binds to DNA cellulose.Science, 234 4782
M. Rea (1989)
Light increases Fos-related protein immunoreactivity in the rat suprachiasmatic nucleiBrain Research Bulletin, 23
F. WILLIAMM., Lee, Chin Lin, Tom Curran (1988)
Activation of the transforming potential of the human fos proto-oncogene requires message stabilization and results in increased amounts of partially modified fos proteinMolecular and Cellular Biology, 8
T. Curran, J. Morgan (1986)
Barium modulates c-fos expression and post-translational modification.Proceedings of the National Academy of Sciences of the United States of America, 83 22
H. Onodera, K. Kogure, Y. Ono, K. Igarashi, Y. Kiyota, A. Nagaoka (1989)
Proto-oncogene c-fos is transiently induced in the rat cerebral cortex after forebrain ischemiaNeuroscience Letters, 98
B. Christy, L. Lau, D. Nathans (1988)
A gene activated in mouse 3T3 cells by serum growth factors encodes a protein with "zinc finger" sequences.Proceedings of the National Academy of Sciences of the United States of America, 85 21
K. Ryder, L. Lau, D. Nathans (1988)
A gene activated by growth factors is related to the oncogene v-jun.Proceedings of the National Academy of Sciences of the United States of America, 85 5
M. Sheng, Grant McFadden, M. Greenberg (1990)
Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREBNeuron, 4
R. Turner, R. Tjian (1989)
Leucine repeats and an adjacent DNA binding domain mediate the formation of functional cFos-cJun heterodimers.Science, 243 4899
J. Morgan, T. Curran (1989)
Stimulus-transcription coupling in neurons: role of cellular immediate-early genesTrends in Neurosciences, 12
C. Abate, D. Luk, T. Curran (1990)
A ubiquitous nuclear protein stimulates the DNA-binding activity of fos and jun indirectly.Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1 10
Tom Curran, William MAcCONNELL, Flip, Van, Straaten, Inder Verma (1983)
Structure of the FBJ murine osteosarcoma virus genome: molecular cloning of its associated helper virus and the cellular homolog of the v-fos gene from mouse and human cellsMolecular and Cellular Biology, 3
E. Bullitt (1989)
Induction of c-fos-like protein within the lumbar spinal cord and thalamus of the rat following peripheral stimulationBrain Research, 493
B. Varnum, R. Lim, Vikas Sukhatme, H. Herschman (1989)
Nucleotide sequence of a cDNA encoding TIS11, a message induced in Swiss 3T3 cells by the tumor promoter tetradecanoyl phorbol acetate.Oncogene, 4 1
D. Stéhelin, H. Varmus, J. Bishop, P. Vogt (1976)
DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNANature, 260
P. Lemaire, O. Revelant, R. Bravo, P. Charnay (1988)
Two mouse genes encoding potential transcription factors with identical DNA-binding domains are activated by growth factors in cultured cells.Proceedings of the National Academy of Sciences of the United States of America, 85 13
RW Presley, D. Menétrey, J. Levine, A. Basbaum (1990)
Systemic morphine suppresses noxious stimulus-evoked Fos protein-like immunoreactivity in the rat spinal cord, 10
M. Dragunow, R. Faull (1989)
The use of c-fos as a metabolic marker in neuronal pathway tracingJournal of Neuroscience Methods, 29
D. Cohen, Paulo Ferreira, Reiner Gentz, B. Franza, T. Curran (1989)
The product of a fos-related gene, fra-1, binds cooperatively to the AP-1 site with Jun: transcription factor AP-1 is comprised of multiple protein complexes.Genes & development, 3 2
George Robertson, D. Herrera, M. Dragunow, H. Robertson (1989)
L-dopa activates c-fos in the striatum ipsilateral to a 6-hydroxydopamine lesion of the substantia nigra.European journal of pharmacology, 159 1
T. Mohun, Nigel Garrett, M. Taylor (1989)
Temporal and tissue-specific expression of the proto-oncogene c-fos during development in Xenopus laevis.Development, 107 4
S. Squinto, A. Block, P. Braquet, N. Bazan (1989)
Platelet‐activating factor stimulates a Fos/Jun/AP‐1 transcriptional signaling system in human neuroblastoma cellsJournal of Neuroscience Research, 24
H. Schröter, P. Shaw, A. Nordheim (1987)
Purification of intercalator-released p67, a polypeptide that interacts specifically with the c-fos serum response element.Nucleic acids research, 15 24
A. Arenander, R. Lim, B. Varnum, R. Cole, J. Vellis, H. Herschman (1989)
TIS gene expression in cultured rat astrocytes: Induction by mitogens and stellation agentsJournal of Neuroscience Research, 23
J. Schütte, J. Viallet, M. Nau, S. Segal, J. Fedorko, J. Minna (1989)
jun-B inhibits and c-fos stimulates the transforming and trans-activating activities of c-junCell, 59
R. Treisman (1985)
Transient accumulation of c-fos RNA following serum stimulation requires a conserved 5′ element and c-fos 3′ sequencesCell, 42
H. Mölders, T. Jenuwein, J. Adamkiewicz, R. Müller (1987)
Isolation and structural analysis of a biologically active chicken c-fos cDNA: identification of evolutionarily conserved domains in fos protein.Oncogene, 1 4
G. Draisci, M. Iadarola (1989)
Temporal analysis of increases in c-fos, preprodynorphin and preproenkephalin mRNAs in rat spinal cord.Brain research. Molecular brain research, 6 1
J. Caubet (1989)
c-fos proto-oncogene expression in the nervous system during mouse developmentMolecular and Cellular Biology, 9
D. Bohmann, T. Bos, A. Admon, T. Nishimura, P. Vogt, R. Tjian (1987)
Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1.Science, 238 4832
P. Shaw, H. Schröter, A. Nordheim (1989)
The ability of a ternary complex to form over the serum response element correlates with serum inducibility of the human c-fos promoterCell, 56
D. Menétrey, A. Gannon, J. Levine, A. Basbaum (1989)
Expression of c‐fos protein in interneurons and projection neurons of the rat spinal cord in response to noxious somatic, articular, and visceral stimulationJournal of Comparative Neurology, 285
R. Gubits, Thomas Smith, Jeanette Fairhurst, Hong Yu (1989)
Adrenergic receptors mediate changes in c-fos mRNA levels in brain.Brain research. Molecular brain research, 6 1
E. Reddy, A. Skalka, T. Curran (1988)
The Oncogene Handbook
T. Maekawa, H. Sakura, C. Kanei-Ishii, T. Sudo, T. Yoshimura, Jun-ichi Fujisawa, Minoru Yoshida, Shunsuke Ishii (1989)
Leucine zipper structure of the protein CRE‐BP1 binding to the cyclic AMP response element in brain.The EMBO Journal, 8
J. Milbrandt (1988)
Nerve growth factor induces a gene homologous to the glucocorticoid receptor geneNeuron, 1
A. Arenander, R. Lim, B. Varnum, R. Cole, J. Vellis, H. Herschman (1989)
Tis gene expression in cultured rat astrocytes: Multiple pathways of induction by mitogensJournal of Neuroscience Research, 23
M. Hayward, R. Duman, E. Nestler (1990)
Induction of the c-fos proto-oncogene during opiate withdrawal in the locus coeruleus and other regions of rat brainBrain Research, 525
F. Lucibello, Carolin Lowag, M. Neuberg, R. Müller (1989)
Trans-repression of the mouse c-fos promoter: A novel mechanism of fos-mediated trans-regulationCell, 59
L. Berkowitz, Karl Riabowol, Michael Gilman (1989)
Multiple sequence elements of a single functional class are required for cyclic AMP responsiveness of the mouse c-fos promoterMolecular and Cellular Biology, 9
Wes Lee, P. Mitchell, R. Tjian (1987)
Purified transcription factor AP-1 interacts with TPA-inducible enhancer elementsCell, 49
F. Tirone, E. Shooter (1989)
Early gene regulation by nerve growth factor in PC12 cells: induction of an interferon-related gene.Proceedings of the National Academy of Sciences of the United States of America, 86 6
M. Gilman, R. Wilson, R. Weinberg (1986)
Multiple protein-binding sites in the 5'-flanking region regulate c-fos expressionMolecular and Cellular Biology, 6
Michael Gilman (1988)
The c-fos serum response element responds to protein kinase C-dependent and -independent signals but not to cyclic AMP.Genes & development, 2 4
S. Williams, A. Pini, G. Evan, S. Hunt (1989)
Molecular Events in the Spinal Cord Following Sensory Stimulation
B. Rusak, Harold Robertson, William Wisden, Stephen Hunt (1990)
Light pulses that shift rhythms induce gene expression in the suprachiasmatic nucleus.Science, 248 4960
R. Douglas, M. Dragunow, H. Robertson (1988)
High-frequency discharge of dentate granule cells, but not long-term potentiation, induces c-fos protein.Brain research, 464 3
A. Minty, L. Kedes (1986)
Upstream regions of the human cardiac actin gene that modulate its transcription in muscle cells: presence of an evolutionarily conserved repeated motifMolecular and Cellular Biology, 6
T. Wilson, Richard Treisman (1988)
Fos C‐terminal mutations block down‐regulation of c‐fos transcription following serum stimulation.The EMBO Journal, 7
M. Subramaniam, L. Schmidt, C. Crutchfield, M. Getz (1989)
Negative regulation of serum-responsive enhancer elementsNature, 340
T. Kouzarides, E. Ziff (1988)
The role of the leucine zipper in the fos–jun interactionNature, 336
K. Fujiwara, K. Ashida, H. Nishina, H. Iba, N. Miyajima, M. Nishizawa, S. Kawai (1987)
The chicken c-fos gene: cloning and nucleotide sequence analysisJournal of Virology, 61
R. Prywes, R. Roeder (1987)
Purification of the c-fos enhancer-binding proteinMolecular and Cellular Biology, 7
C. Ruppert, W. Wille (1987)
Proto-oncogene c-fos is highly induced by disruption of neonatal but not of mature brain tissue.Brain research, 388 1
P. Vogt, T. Bos, R. Doolittle (1987)
Homology between the DNA-binding domain of the GCN4 regulatory protein of yeast and the carboxyl-terminal region of a protein coded for by the oncogene jun.Proceedings of the National Academy of Sciences of the United States of America, 84 10
One of the major challenges confronting modern biologists is to delineate the molecular mechanisms by which cells adapt their phenotype in response to environmental signals. Although much has been learned about the rapid and short-lived changes that occur following stimulation, relatively little is known about the processes that convert ephemeral second messenger mediated events into long-term cellular phenotypic alterations. This ques tion is of particular relevance to the neurobiologist, who must explain how brief stimulation of neurons can lead to changes in function that can persist for the lifetime of the animal. Although there are no simple answers, recently neurobiologists have been aided in their quest by concepts and reagents borrowed from the field of oncogene research. In particular, the proto-oncogene Jos has provided a novel avenue for research and a useful marker with which the effects of pharmacological, electrical, and physiologicaf stimuli may be traced in the nervous system. Here we summarize the origin and function ofJos and the set of inducible genes to 421 o 1 47-D06Xj 9 1j030 I-D421 $02.00 MORGAN & CURRAN which it belongs, and we review the literature concerning its advent in the neurosciences. THE ORIGIN OF ONCOGENES Oncogenes were first described
Annual Review of Neuroscience – Annual Reviews
Published: Mar 1, 1991
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