Access the full text.
Sign up today, get DeepDyve free for 14 days.
A. Ladurner (2003)
Inactivating chromosomes: a macro domain that minimizes transcription.Molecular cell, 12 1
M. Miwa, T. Sugimura (1971)
Splitting of the ribose-ribose linkage of poly(adenosine diphosphate-robose) by a calf thymus extract.The Journal of biological chemistry, 246 20
A. Ladurner, C. Inouye, Rajan Jain, R. Tjian (2003)
Bromodomains mediate an acetyl-histone encoded antisilencing function at heterochromatin boundaries.Molecular cell, 11 2
Michael McClelland, K. Sanderson, J. Spieth, S. Clifton, P. Latreille, L. Courtney, S. Porwollik, Johar Ali, M. Dante, Feiyu Du, Shunfang Hou, Daniel Layman, S. Leonard, Christine Nguyen, Kelsi Scott, Andrea Holmes, Neenu Grewal, E. Mulvaney, E. Ryan, Hui Sun, L. Florea, W. Miller, T. Stoneking, M. Nhan, R. Waterston, R. Wilson (2001)
Complete genome sequence of Salmonella enterica serovar Typhimurium LT2Nature, 413
K. Novak (1998)
The complete genome sequence…Nature Medicine, 4
A. Chiarugi (2002)
Poly(ADP-ribose) polymerase: killer or conspirator? The 'suicide hypothesis' revisited.Trends in pharmacological sciences, 23 3
J. Amé, C. Spenlehauer, G. Murcia (2004)
The PARP superfamilyBioEssays, 26
R. Story, T. Steitz (1992)
Structure of the recA protein–ADP complexNature, 355
K. Luger, T. Rechsteiner, A. Flaus, M. Waye, T. Richmond (1997)
Characterization of nucleosome core particles containing histone proteins made in bacteria.Journal of molecular biology, 272 3
Frédéric Simonin, Olivier Poch, Marc Delarue, G. Murcia (1993)
Identification of potential active-site residues in the human poly(ADP-ribose) polymerase.The Journal of biological chemistry, 268 12
L. Aravind (2001)
The WWE domain: a common interaction module in protein ubiquitination and ADP ribosylation.Trends in biochemical sciences, 26 5
C. Szab (2002)
The Therapeutic Potential of Poly(ADP-Ribose) Polymerase Inhibitors
P. Panzeter, F. Althaus (1990)
High resolution size analysis of ADP-ribose polymers using modified DNA sequencing gels.Nucleic acids research, 18 8
P. Hassa, M. Hottiger (1999)
A Role of Poly (ADP-Ribose) Polymerase in NF- B Transcriptional Activation, 380
M. Ikejima, S. Noguchi, R. Yamashita, T. Ogura, T. Sugimura, D. Gill, M. Miwa (1990)
The zinc fingers of human poly(ADP-ribose) polymerase are differentially required for the recognition of DNA breaks and nicks and the consequent enzyme activation. Other structures recognize intact DNA.The Journal of biological chemistry, 265 35
M. Rouleau, R. Aubin, G. Poirier (2004)
Poly(ADP-ribosyl)ated chromatin domains: access grantedJournal of Cell Science, 117
M. Cohen-Armon, L. Visochek, A. Katzoff, D. Levitan, Abraham Susswein, R. Klein, Mireille Valbrun, J. Schwartz (2004)
Long-Term Memory Requires PolyADP-ribosylationScience, 304
L. Davidovic, M. Vodenicharov, E. Affar, G. Poirier (2001)
Importance of poly(ADP-ribose) glycohydrolase in the control of poly(ADP-ribose) metabolism.Experimental cell research, 268 1
Pehrson, VA Fried (1992)
MacroH2A, a core histone containing a large nonhistone region.Science, 257 5075
E. Winstall, E. Affar, R. Shah, S. Bourassa, A. Scovassi, G. Poirier (1999)
Poly(ADP-ribose) glycohydrolase is present and active in mammalian cells as a 110-kDa protein.Experimental cell research, 246 2
Jasmin Dynek, Susan Smith (2004)
Resolution of Sister Telomere Association Is Required for Progression Through MitosisScience, 304
Ricardo Aguiar, Yoshihiro Yakushijin, Samir Kharbanda, Ravi Salgia, Jonathan Fletcher, M. Shipp (2000)
BAL is a novel risk-related gene in diffuse large B-cell lymphomas that enhances cellular migration.Blood, 96 13
S Hanai, M Kanai, S Ohashi, K Okamoto, M Yamada, H Takahashi, M Miwa (2004)
Loss of poly(ADP‐ribose) glycohydrolase causes progressive neurodegeneration in Drosophila melanogasterBiol Chem, 101
BD Cook, JN Dynek, W Chang, G Shostak, S Smith (2002)
Role for the related poly(ADP‐Ribose) polymerases tankyrase 1 and 2 at human telomeresEMBO J, 22
A. Wallace, R. Laskowski, J. Thornton (1995)
LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions.Protein engineering, 8 2
K. Luger, T. Rechsteiner, T. Richmond (1999)
Preparation of nucleosome core particle from recombinant histones.Methods in enzymology, 304
R. Jacobson, A. Ladurner, D. King, R. Tjian (2000)
Structure and function of a human TAFII250 double bromodomain module.Science, 288 5470
Brandoch Cook, Jasmin Dynek, William Chang, Grigoriy Shostak, Susan Smith (2002)
Role for the Related Poly(ADP-Ribose) Polymerases Tankyrase 1 and 2 at Human TelomeresMolecular and Cellular Biology, 22
B. Durkacz, O. Omidiji, D. Gray, S. Shall (1980)
(ADP-ribose)n participates in DNA excision repairNature, 283
Daniela Corda, Maria Girolamo (2003)
Functional aspects of protein mono‐ADP‐ribosylationThe EMBO Journal, 22
L. Virág, C. Szabó (2002)
The Therapeutic Potential of Poly(ADP-Ribose) Polymerase InhibitorsPharmacological Reviews, 54
Susan Smith, Izabela Giriat, A. Schmitt, T. Lange (1998)
Tankyrase, a poly(ADP-ribose) polymerase at human telomeres.Science, 282 5393
Axel Brüngera, Paul Adamsb, G. Clorec, Warren DeLanod, Piet Grose, Ralf Grosse-Kunstlevea, Jian-Sheng Jiangf, John Kuszewskic, Michael Nilgesg, Navraj Pannuh, Randy Readi, Luke Riceb, Thomas Simonsonj, Gregory Warrenb (1998)
Crystallography & NMR system: A new software suite for macromolecular structure determination.Acta crystallographica. Section D, Biological crystallography, 54 Pt 5
R. Benjamin, D. Gill (1980)
Poly(ADP-ribose) synthesis in vitro programmed by damaged DNA. A comparison of DNA molecules containing different types of strand breaks.The Journal of biological chemistry, 255 21
J. Weill, S. Busch, P. Chambon, P. Mandel (1963)
The effect of estradiol injections upon chicken liver nuclei ribonucleic acid polymerase.Biochemical and biophysical research communications, 10
S. Hanai, M. Kanai, Sayaka Ohashi, K. Okamoto, M. Yamada, H. Takahashi, M. Miwa (2003)
Loss of poly(ADP-ribose) glycohydrolase causes progressive neurodegeneration in Drosophila melanogasterProceedings of the National Academy of Sciences of the United States of America, 101
(1991)
Recent Changes to the MOSFLM Package for Processing of Image-Plate Data
緒方 規男 (1980)
ADP-ribosylation of histone HI
G. Culver, S. McCraith, M. Zillmann, R. Kierzek, N. Michaud, R. Lareau, D. Turner, E. Phizicky (1993)
An NAD derivative produced during transfer RNA splicing: ADP-ribose 1"-2" cyclic phosphate.Science, 261 5118
M. Cervellera, A. Sala (2000)
Poly(ADP-ribose) Polymerase Is a B-MYB Coactivator*The Journal of Biological Chemistry, 275
M. Martzen, S. McCraith, S. Spinelli, Francy Torres, S. Fields, E. Grayhack, E. Phizicky (1999)
A biochemical genomics approach for identifying genes by the activity of their products.Science, 286 5442
G. Krupitza, P. Cerutti (1989)
Poly(ADP-ribosylation) of histones in intact human keratinocytes.Biochemistry, 28 9
J. Rippmann, K. Damm, A. Schnapp (2002)
Functional characterization of the poly(ADP-ribose) polymerase activity of tankyrase 1, a potential regulator of telomere length.Journal of molecular biology, 323 2
Collaborative Computational (1994)
The CCP4 suite: programs for protein crystallography.Acta crystallographica. Section D, Biological crystallography, 50 Pt 5
Xuetong Shen, Hua Xiao, R. Ranallo, Wei-Hua Wu, Carl Wu (2002)
Modulation of ATP-Dependent Chromatin-Remodeling Complexes by Inositol PolyphosphatesScience, 299
S. Beneke, J. Diefenbach, A. Bürkle (2004)
Poly(ADP‐ribosyl)ation inhibitors: Promising drug candidates for a wide variety of pathophysiologic conditionsInternational Journal of Cancer, 111
P. Adamietz, A. Rudolph (1984)
ADP-ribosylation of nuclear proteins in vivo. Identification of histone H2B as a major acceptor for mono- and poly(ADP-ribose) in dimethyl sulfate-treated hepatoma AH 7974 cells.The Journal of biological chemistry, 259 11
Armin Ruf, V. Rolli, G. Murcia, Georg Schulz (1998)
The mechanism of the elongation and branching reaction of poly(ADP-ribose) polymerase as derived from crystal structures and mutagenesis.Journal of molecular biology, 278 1
H. Kim, M. Jacobson, V. Rolli, J. murcia, J. Reinbolt, F. Simonin, A. Ruf, G. Schulz, G. Murcia (1997)
Photoaffinity labelling of human poly(ADP-ribose) polymerase catalytic domain.The Biochemical journal, 322 ( Pt 2)
D D'Amours, S Desnoyers, I D'Silva, GG Poirier (1999)
Poly(ADP‐ribosyl)ation reactions in the regulation of nuclear functionsExp Cell Res, 342
AG Ladurner, C Inouye, R Jain, R Tjian (2003)
Bromodomains mediate an acetyl‐histone encoded antisilencing function at heterochromatin boundariesNucleic Acids Res, 11
M. Kim, Steven Mauro, N. Gevry, J. Lis, W. Kraus (2004)
NAD+-Dependent Modulation of Chromatin Structure and Transcription by Nucleosome Binding Properties of PARP-1Cell, 119
P. Chambon, J. Weill, P. Mandel (1963)
Nicotinamide mononucleotide activation of new DNA-dependent polyadenylic acid synthesizing nuclear enzyme.Biochemical and biophysical research communications, 11
D. Steger, E. Haswell, A. Miller, S. Wente, E. O’Shea (2002)
Regulation of Chromatin Remodeling by Inositol PolyphosphatesScience, 299
A. Saxena, L. Wong, P. Kalitsis, E. Earle, L. Shaffer, K. Choo (2002)
Poly(ADP-ribose) polymerase 2 localizes to mammalian active centromeres and interacts with PARP-1, Cenpa, Cenpb and Bub3, but not Cenpc.Human molecular genetics, 11 19
W. Kraus, J. Lis (2003)
PARP Goes TranscriptionCell, 113
D. Owen, Prisca Ornaghi, Ji-Chun Yang, Nicholas Lowe, P. Evans, P. Ballario, D. Neuhaus, P. Filetici, A. Travers (2000)
The structural basis for the recognition of acetylated histone H4 by the bromodomain of histone acetyltransferase Gcn5pThe EMBO Journal, 19
XY Guan, JST Sham (2003)
Homo sapiens ALC1 mRNAProc Natl Acad Sci USA
E. Earle, A. Saxena, Andrew MacDonald, D. Hudson, L. Shaffer, R. Saffery, M. Cancilla, S. Cutts, E. Howman, K. Choo (2000)
Poly(ADP-ribose) polymerase at active centromeres and neocentromeres at metaphase.Human molecular genetics, 9 2
D. D'Amours, S. Desnoyers, I. D’Silva, G. Poirier (1999)
Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions.The Biochemical journal, 342 ( Pt 2)
A. Tulin, A. Spradling (2003)
Chromatin Loosening by Poly(ADP)-Ribose Polymerase (PARP) at Drosophila Puff LociScience, 299
R. Schoenfeld (1976)
Comparative Genomics of Listeria SpeciesScience, 294
JP Abrahams, AGW Leslie, R Lutter, JE Walker (1994)
Structure at 2.8 Angstrom resolution of the F1‐ATPase from bovine heart mitochondriaNature, 370
Wenqiang Yu, V. Ginjala, V. Pant, I. Chernukhin, J. Whitehead, F. Docquier, D. Farrar, Gholamreza Tavoosidana, Rituparna Mukhopadhyay, C. Kanduri, M. Oshimura, A. Feinberg, V. Lobanenkov, E. Klenova, R. Ohlsson (2004)
Poly(ADP-ribosyl)ation regulates CTCF-dependent chromatin insulationNature Genetics, 36
B. Chadwick, H. Willard (2001)
Histone H2A variants and the inactive X chromosome: identification of a second macroH2A variant.Human molecular genetics, 10 10
E. Winstall, E. Affar, R. Shah, S. Bourassa, I. Scovassi, G. Poirier (1999)
Preferential perinuclear localization of poly(ADP-ribose) glycohydrolase.Experimental cell research, 251 2
Guy Poirier, C. Niedergang, Madeleine Champagne, Alice Mazen, Paul Mandel (2005)
Adenosine diphosphate ribosylation of chicken-erythrocyte histones H1, H5 and high-mobility-group proteins by purified calf-thymus poly(adenosinediphosphate-ribose) polymerase.European journal of biochemistry, 127 3
P. Hassa, M. Hottiger (1999)
A role of poly (ADP-ribose) polymerase in NF-kappaB transcriptional activation.Biological chemistry, 380 7-8
P. Chang, M. Jacobson, T. Mitchison (2004)
Poly(ADP-ribose) is required for spindle assembly and structureNature, 432
(1994)
The CCP4 suite: programs for protein crystallographyMol Cell Biol, 50
N. Ogata, K. Ueda, H. Kagamiyama, O. Hayaishi (1980)
ADP-ribosylation of histone H1. Identification of glutamic acid residues 2, 14, and the COOH-terminal lysine residue as modification sites.The Journal of biological chemistry, 255 16
M. Allen, A. Buckle, S. Cordell, J. Löwe, M. Bycroft (2003)
The crystal structure of AF1521 a protein from Archaeoglobus fulgidus with homology to the non-histone domain of macroH2A.Journal of molecular biology, 330 3
M. Malanga, J. Pleschke, H. Kleczkowska, F. Althaus (1998)
Poly(ADP-ribose) Binds to Specific Domains of p53 and Alters Its DNA Binding Functions*The Journal of Biological Chemistry, 273
J. Abrahams, A. Leslie, R. Lutter, J. Walker (1994)
Structure at 2.8 Â resolution of F1-ATPase from bovine heart mitochondriaNature, 370
C. Dhalluin, Justin Carlson, L. Zeng, Cheng He, A. Aggarwal, Ming-Ming Zhou (1999)
Structure and ligand of a histone acetyltransferase bromodomainNature, 399
P. Panzeter, C. Realini, F. Althaus (1992)
Noncovalent interactions of poly(adenosine diphosphate ribose) with histones.Biochemistry, 31 5
Cary Bauer, M. Fonseca, H. Holden, J. Thoden, Thomas Thompson, J. Escalante‐Semerena, I. Rayment (2001)
Three-dimensional structure of ATP:corrinoid adenosyltransferase from Salmonella typhimurium in its free state, complexed with MgATP, or complexed with hydroxycobalamin and MgATP.Biochemistry, 40 2
Wensheng Lin, J. Amé, N. Aboul-ela, E. Jacobson, M. Jacobson (1997)
Isolation and Characterization of the cDNA Encoding Bovine Poly(ADP-ribose) Glycohydrolase*The Journal of Biological Chemistry, 272
Ivica Letunic, R. Copley, Steffen Schmidt, F. Ciccarelli, T. Doerks, J. Schultz, C. Ponting, P. Bork (2004)
SMART 4.0: towards genomic data integrationNucleic acids research, 32 Database issue
J. Pleschke, H. Kleczkowska, M. Strohm, F. Althaus (2000)
Poly(ADP-ribose) Binds to Specific Domains in DNA Damage Checkpoint Proteins*The Journal of Biological Chemistry, 275
The ADP‐ribosylation of proteins is an important post‐translational modification that occurs in a variety of biological processes, including DNA repair, transcription, chromatin biology and long‐term memory formation. Yet no protein modules are known that specifically recognize the ADP‐ribose nucleotide. We provide biochemical and structural evidence that macro domains are high‐affinity ADP‐ribose binding modules. Our structural analysis reveals a conserved ligand binding pocket among the macro domain fold. Consistently, distinct human macro domains retain their ability to bind ADP‐ribose. In addition, some macro domain proteins also recognize poly‐ADP‐ribose as a ligand. Our data suggest an important role for proteins containing macro domains in the biology of ADP‐ribose.
The EMBO Journal – Wiley
Published: Jan 1, 2005
Keywords: ; ; ; ;
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.